Microtubule structure in nervous system repair

神经系统修复中的微管结构

• 批准号: DP200102187
• 负责人: Dr Brent Neumann
• 金额: $ 36.52万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200102187
• 关键词: Microtubule; structure; nervous; system; repair

This Project aims to investigate the role of structural and functional cellular components known as microtubules in nervous system regeneration. This Project aims to use innovative approaches in confocal and electron microscopy, genetics, and cell biology, with the expectation of generating new knowledge into nervous system repair. Expected outcomes of this Project include a comprehensive description of how microtubules are rearranged following nervous system injury and the importance of microtubule modifying proteins in promoting regeneration. This should provide significant benefits in our understanding of the cellular mechanisms behind nervous system repair, and offer new approaches for promoting regeneration after injury.

该项目旨在研究被称为微管的结构和功能细胞组件在神经系统再生中的作用。该项目旨在使用共聚焦和电子显微镜、遗传学和细胞生物学的创新方法，期望在神经系统修复中产生新的知识。该项目的预期成果包括全面描述神经系统损伤后微管如何重排，以及微管修饰蛋白在促进再生方面的重要性。这将为我们理解神经系统修复背后的细胞机制提供显著的益处，并为促进损伤后的再生提供新的途径。