CENTER FOR ADVANCED MEDICAL INFORMATICS

我们建议创建共享计算资源来支持研究 斯坦福大学医学院生物医学信息学活动 医学。学校成立了先进医学中心 斯坦福大学信息学(CAMIS)，它将学术、行政、 和研究计算。申请的资金将支持一个活跃的核心 研究计划以及基础设施和日常计算需求 一大批研究人员，每个人都得到了NIH的外部支持 或其他机构通过赠款或合同。没有单一的研究小组 可以支持一组复杂的基础架构和系统功能 上世纪90年代需要进行高级医学信息学研究的S。 我们设计、管理和构建CAMIS资源的方法将 以若干总体目标为指导：(1)培育科学的 在分布式研究中实现通信、协作和共享 环境；(2)为探索生物医学提供一流的环境 信息学专题；(3)追求强大的基础复制系统；(4) 以帮助定义传播计算和 将信息管理技术融入现实世界；以及(5) 为我们的客户创造最先进的计算和通信环境 研究工作。 这项工作的具体目标分为四类： 定义CAMIS资源的功能： 核心研究和开发：我们正在提出核心研究项目 以下几个领域：(1)临床试验工作站(CTW)项目-推广 并将系统设计概念和实现解决方案从我们的 ONCOCIN和T-HELPER项目，以便它们可以应用于促进 年发展最快的综合临床试验工作站 临床试验管理的任何领域；(2)了解 生物分子--开发和推广改进的工具 发现并理解结构关系，以便这些 用于理解基因组图谱中识别的基因的功能 调查；(3)高级计算系统和环境--建立在 广泛的分布式计算环境已经到位，并且 根据需要改进、扩展和调整新的计算工具，以支持 卡米斯社区。具体的系统研究领域包括基于手势的 便携式计算信息资源导航和检索工具， 电子邮件管理工具、高速网络、大容量文件存储、 和新的工作站技术。 协作研究：大型研究人员社区将 在CAMIS资源的支持下，从事临床等领域的工作 试验方案管理、不确定推理方法 生物信息学、卫生保健结果和经济学、基础人工 情报研究、人机界面、多媒体创作和 医学教育项目的交付工具和分布式图书馆 资源。因此，我们将通过改进 集团内部和集团内通信的机制。 服务和资源运营：CAMI将有效和广泛地提供 无障碍通信和计算设施、咨询服务、 和管理支持，并将以咨询身份为医疗 学校行政部门。 培训、教育和传播：CAMIS将强调强大的用户 在其设施管理定位方面，将继续办好两个正式 研究生学位课程(一个是医学信息学，一个是健康 服务研究)，并将积极通过 出版物、软件出口、视频演示、访问学者 计划，以及一年一度的CAMIS研讨会。

We propose creating a shared computing resource to support research activities in biomedical informatics at the Stanford University School of Medicine. The School has established the Center for Advanced Medical Informatics at Stanford (CAMIS), which unites academic, administrative, and research computing. The requested funds will support an active core research program and the infrastructure and day-to-day computing needs of a large number of researchers, each of whom has external support from NIH or other agencies through grants or contracts. No single research group could support the complex set of infrastructural and system capabilities needed to conduct advanced medical informatics research in the 1990's. Our approach to designing, managing, and building the CAMIS resource will be guided by a number of overall goals: (1) to foster scientific communication, collaboration, and sharing within a distributed research environment; (2) to provide a superb setting for exploring biomedical informatics topics; (3) to pursue a strong basic replications systems; (4) to help define new ways to disseminate computing and information-management technologies into real-world settings; and (5) to create a state-of-the-art computing and communication environment for our research work. The specific aims for this undertaking fall under four categories that define the functions of the CAMIS resources: Core Research and Development: We are proposing core research projects in several areas: (1) Clinical Trials Workstation (CTW) Project-generalize and abstract system-design concepts and implementation solutions from our ONCOCIN and T-HELPER projects so that they can be applied to facilitate the most rapid development of integrated clinical-trials workstations in any domain of clinical-trials management; (2) Understanding the Code for Biological Molecules--development and generalize improved tools for discovering and for understanding the structure relationships so these can be used to understand the functions of genes identified in genome mapping investigation; (3) Advanced Computing Systems and Environments--build upon the extensive distributed-computing environment already in place and improve, extend, and adapt new computing tools as necessary to support the CAMIS community. Specific systems research areas include gesture-based portable computing information resource navigation and retrieval tools, email management tools, high-speed networks, large-volume file storage, and new workstations technologics. Collaborative Research: A large community of researchers will be supported by the CAMIS resource, doing work in areas such as clinical trial protocol management, methods for uncertain reasoning, bioinformatics, health care outcomes and economics, basic artificial intelligence research, human-computer interfaces, multimedia authoring and delivery tools for medical education programs, and distributed library resources. We will accordingly encourage collaborations through improved mechanisms for inter- and intra-group communications. Service and Resource Operations: CAMIS will provide effective and widely accessible communication and computing facilities, consulting services, and managerial support and will serve in an advisory capacity to Medical School administration. Training, Education, and Dissemination: CAMIS will emphasize a strong user orientation in its facilities management, will continue to run two formal graduate degree programs (one in medical informatics and one in health services research), and will actively disseminate research results through publications, software exports, video presentations, visiting scholar programs, and an annual CAMIS Symposium.