Utilisation of Electrodialysis membranes for the recovery of amino acids from enzymatic reaction mixtures-(EDAM).

利用电渗析膜从酶反应混合物（EDAM）中回收氨基酸。

• 批准号: 131523
• 金额: $ 17.28万
• 依托单位: CHIROTECH TECHNOLOGY LIMITED
• 依托单位国家: 英国
• 项目类别: Feasibility Studies
• 财政年份: 2014
• 资助国家: 英国
• 起止时间: 2014 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=131523
• 关键词: Utilisation; Electrodialysis; membranes; recovery; amino

The purpose of the EDAM project is to test the feasibility of combining two well established technologies in order to develop an innovative process for the production and isolation of amino acids. Biocatalysis is a well established technology in the chemical and pharmaceutical industries, allowing the conversion of an amino acid precursor into a target amino acid using 1 or 2 enzymes. Electrodialysis membranes have been used for many years in the water purification industry, however wider applications of this technology remain under utilised. We propose to utilise a two enzyme reaction system to facilitate the production of amino acids. Subsequent application of a direct current electric field to the reaction mixture will then lead to electromigration of the charged amino acid species across an ion exchange membrane and product purification.

埃达姆项目的目的是测试结合两种成熟技术的可行性，以开发氨基酸生产和分离的创新工艺。生物催化是化学和制药工业中成熟的技术，允许使用1或2种酶将氨基酸前体转化为目标氨基酸。电渗析膜已在水净化行业中使用多年，然而该技术的更广泛应用仍未得到充分利用。我们建议利用双酶反应系统来促进氨基酸的生产。随后向反应混合物施加直流电场将导致带电氨基酸物质电迁移穿过离子交换膜和产物纯化。