Revealing the determinants of viral emergence and evolution in fish

揭示鱼类病毒出现和进化的决定因素

• 批准号: DP200102351
• 负责人: Prof Edward Holmes
• 金额: $ 39.22万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-03-01 至 2023-09-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200102351
• 关键词: Revealing; determinants; viral; emergence; evolution

Viral diseases pose an ongoing threat to Australian aquaculture. The devastating impact of emerging viruses makes it imperative to understand the factors that allow them to evolve and infect new hosts. We will address these key issues by revealing the diversity, abundance and evolution of viruses in fish sampled along the Australian east coast. The data generated will reveal the untapped biodiversity of fish viruses, the frequency which they jump species boundaries and the determinants of this process, and how they are impacted by host ecology, including whether fish viruses follow a latitudinal gradient in diversity. The data generated will transform our understanding of fish viruses and identify those most likely to impact aquaculture.

病毒性疾病对澳大利亚水产养殖业构成持续威胁。新出现的病毒的破坏性影响使得我们必须了解使它们进化并感染新宿主的因素。我们将通过揭示沿着澳大利亚东海岸鱼类样本中病毒的多样性、丰度和进化来解决这些关键问题。所产生的数据将揭示鱼类病毒尚未开发的生物多样性，它们跨越物种边界的频率和这一过程的决定因素，以及它们如何受到宿主生态的影响，包括鱼类病毒是否遵循多样性的纬度梯度。所产生的数据将改变我们对鱼类病毒的理解，并确定最有可能影响水产养殖的病毒。