Silver Antimicrobial Surface for Improved Performance of Complex Orthopaedic Implant Technologies

银抗菌表面可提高复杂骨科植入技术的性能

• 批准号: 132896
• 金额: $ 11.76万
• 依托单位: ACCENTUS MEDICAL LIMITED
• 依托单位国家: 英国
• 项目类别: Feasibility Studies
• 财政年份: 2017
• 资助国家: 英国
• 起止时间: 2017 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=132896
• 关键词: Silver; Antimicrobial; Surface; Improved; Performance

The project will develop and evaluate a novel silver based anti-microbial surface treatment for application to complex orthopaedic device materials. The project will build on Accentus Medical's previous successful commercialisation of its proprietary Agluna® silver ion based anti-microbial technology for conventional titanium orthopaedic device surfaces. The current project is driven by recent market trend towards more complex device materials, such as 3-D porous structures formed by e.g. additive layer manufacturing techniques. With the clinical performance demonstrated by Agluna® in reducing the incidence and severity of post-operative infections with conventional device substrates, Accentus Medical is now seeking to address evolving market demand for a novel silver based antimicrobial surface treatment applied to more complex substrates. The project will demonstrate the basic safety and efficacy characteristics required of a viable surface technology, as well as the potential for the selected surface technology to be amenable to rigorous manufacturing process control requirements of the highly regulated orthopaedic device industry.

该项目将开发和评估一种新型的银基抗微生物表面处理方法，应用于复杂的骨科设备材料。该项目将建立在埃森哲医疗公司之前成功商业化其专有的、基于银离子的抗微生物技术的基础上，该技术用于传统钛矫形设备表面。目前的项目是由最近更复杂的器件材料的市场趋势推动的，例如通过附加层制造技术形成的3D多孔结构。凭借Agluna®在降低传统设备基材术后感染发生率和严重程度方面的临床表现，埃森哲医疗集团现在正在寻求满足市场对适用于更复杂基材的新型银基抗菌表面处理的不断变化的需求。该项目将展示可行的表面技术所需的基本安全和功效特性，以及所选表面技术符合高度监管的整形外科设备行业严格的制造过程控制要求的潜力。