Silver Antimicrobial Surface for Improved Performance of Complex Orthopaedic Implant Technologies

该项目将开发和评价一种新型银基抗菌表面处理，用于复杂骨科器械材料。该项目将建立在Accentus Medical之前成功商业化其专有的Agluna®银离子抗菌技术的基础上，该技术用于传统的钛骨科器械表面。目前的项目是由最近的市场趋势，更复杂的设备材料，如3D多孔结构形成的增材层制造技术。由于Agluna®在降低传统器械基质术后感染的发生率和严重程度方面的临床性能得到证实，Accentus Medical目前正在寻求解决应用于更复杂基质的新型银基抗菌表面处理的不断变化的市场需求。该项目将证明可行表面技术所需的基本安全性和有效性特征，以及所选表面技术符合高度监管的骨科器械行业严格制造过程控制要求的潜力。

The project will develop and evaluate a novel silver based anti-microbial surface treatment for application to complex orthopaedic device materials. The project will build on Accentus Medical's previous successful commercialisation of its proprietary Agluna® silver ion based anti-microbial technology for conventional titanium orthopaedic device surfaces. The current project is driven by recent market trend towards more complex device materials, such as 3-D porous structures formed by e.g. additive layer manufacturing techniques. With the clinical performance demonstrated by Agluna® in reducing the incidence and severity of post-operative infections with conventional device substrates, Accentus Medical is now seeking to address evolving market demand for a novel silver based antimicrobial surface treatment applied to more complex substrates. The project will demonstrate the basic safety and efficacy characteristics required of a viable surface technology, as well as the potential for the selected surface technology to be amenable to rigorous manufacturing process control requirements of the highly regulated orthopaedic device industry.