SUstainable nanoPaRticles Enabled antiMicrobial surfacE coatings (SUPREME)
可持续纳米颗粒抗菌表面涂层 (SUPREME)
基本信息
- 批准号:10066323
- 负责人:
- 金额:$ 14.43万
- 依托单位:
- 依托单位国家:英国
- 项目类别:EU-Funded
- 财政年份:2023
- 资助国家:英国
- 起止时间:2023 至 无数据
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
The catastrophic ongoing pandemic has attracted our attention towards the spread of harmful pathogens facilitated by high traffic surfaces, highlighting the importance and urgency of an economically and environmentally sustainable solution for antimicrobial surface as a potential strategy to mitigate the spread of disease outbreaks. Nanoparticle (NP) filled coatings, with recognised effectiveness against bacteria, viruses, and fungi, are valuable candidatesfor developing antimicrobialsurface and minimising the surface adhesion of pathogens. However, due to the many technical challenges, including difficulty to develop nanocoatings with a long-term antimicrobial capability, durability under real conditions and safety assurance, their application at industrial level is still limited. The SUPREME consortium will develop a platform of efficient and multifunctional antimicrobial nanocoatings, building upon bespoke TiO2 nanoparticles that have demonstrated an exceptional antimicrobial ability at lab scale (TRL3). Two sustainable routes: 1) customised core/shell and advanced functional nanoparticles and 2) hybrid fibre-nanoparticles (using sustainable bio-based cellulose materials and nanoparticles) will be pursued. Bearing in mind the specific requirements of individual applications, the SUPREME consortium will coordinate the antimicrobial testings to its effectiveness against a wide range of pathogens. The production of the SUPREME coating will follow a sustainable-by-design approach that considers both toxicity and environmental impact from outset to guarantee both market acceptance and sustainability of the overall process whilst having a robust safety assurance in place for human health. The scaling-up production of these sustainable materials and their validation according to the industrial requirements will enable to reach the TRL6 by the end of the project.
灾难性的持续流行引起了我们对高交通路面促进的有害病原体传播的关注,突出了经济和环境可持续的抗菌表面解决方案的重要性和紧迫性,作为减缓疾病爆发传播的潜在战略。纳米颗粒(NP)填充涂层具有公认的抗细菌、病毒和真菌的有效性,是开发抗菌表面和最大限度地减少病原体表面粘附的有价值的候选材料。然而,由于许多技术挑战,包括难以开发具有长期抗微生物能力、在真实的条件下的耐久性和安全保证的纳米涂层,它们在工业水平上的应用仍然受到限制。SUPREME联盟将开发一个高效和多功能抗菌纳米涂层平台,该平台以定制的TiO 2纳米颗粒为基础,这些纳米颗粒在实验室规模(TRL 3)中表现出卓越的抗菌能力。两条可持续发展路线:1)定制的核/壳和先进的功能性纳米粒子和2)混合纤维纳米粒子(使用可持续的生物基纤维素材料和纳米粒子)将被追求。考虑到个别应用的具体要求,SUPREME联盟将协调抗菌测试,以确保其对各种病原体的有效性。SUPREME涂料的生产将遵循可持续的设计方法,从一开始就考虑毒性和环境影响,以确保整个过程的市场接受度和可持续性,同时为人类健康提供强大的安全保证。这些可持续材料的规模化生产及其根据工业要求进行的验证将使其在项目结束时达到TRL 6。
项目成果
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其他文献
吉治仁志 他: "トランスジェニックマウスによるTIMP-1の線維化促進機序"最新医学. 55. 1781-1787 (2000)
Hitoshi Yoshiji 等:“转基因小鼠中 TIMP-1 的促纤维化机制”现代医学 55. 1781-1787 (2000)。
- DOI:
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LiDAR Implementations for Autonomous Vehicle Applications
- DOI:
- 发表时间:
2021 - 期刊:
- 影响因子:0
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吉治仁志 他: "イラスト医学&サイエンスシリーズ血管の分子医学"羊土社(渋谷正史編). 125 (2000)
Hitoshi Yoshiji 等人:“血管医学与科学系列分子医学图解”Yodosha(涉谷正志编辑)125(2000)。
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Effect of manidipine hydrochloride,a calcium antagonist,on isoproterenol-induced left ventricular hypertrophy: "Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,K.,Teragaki,M.,Iwao,H.and Yoshikawa,J." Jpn Circ J. 62(1). 47-52 (1998)
钙拮抗剂盐酸马尼地平对异丙肾上腺素引起的左心室肥厚的影响:“Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,
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