C-H to C-F using electrochemistry and gold catalysis

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Gold offers great potential in chemical catalysis and this project will use a fascinating new class of gold compounds discovered by the CIs, to develop novel catalysts. Using this chemistry a series of gold(III) compounds with fluoride ligands will be prepared. The catalytic properties of these molecules will then be explored, with a particular focus on adding value to arene hydrocarbons. The ultimate goal of the project is development of new catalysts for the formation of carbon-fluorine bonds and the selective fluorination of organic compounds. Fluorinated organic molecules are of critical importance in medicinal chemistry and new catalysts of this type offers the potential for better synthesis of medicines and diagnostic agents.