C-H to C-F using electrochemistry and gold catalysis

金在化学催化方面具有巨大的潜力，该项目将使用独联体发现的一类迷人的新型金化合物来开发新型催化剂。利用这种化学方法，将制备一系列含氟配体的金(III)化合物。然后将探索这些分子的催化性能，特别是增加芳烃的价值。该项目的最终目标是开发用于碳-氟键形成和有机选择性氟化的新催化剂。 化合物。含氟有机分子在药物化学中起着至关重要的作用，这类新型催化剂为更好地合成药物和诊断试剂提供了可能性。

Gold offers great potential in chemical catalysis and this project will use a fascinating new class of gold compounds discovered by the CIs, to develop novel catalysts. Using this chemistry a series of gold(III) compounds with fluoride ligands will be prepared. The catalytic properties of these molecules will then be explored, with a particular focus on adding value to arene hydrocarbons. The ultimate goal of the project is development of new catalysts for the formation of carbon-fluorine bonds and the selective fluorination of organic compounds. Fluorinated organic molecules are of critical importance in medicinal chemistry and new catalysts of this type offers the potential for better synthesis of medicines and diagnostic agents.