SCANNER VALIDATION FOR INVERSE SCATTERING BREAST IMAGING

逆散射乳腺成像的扫描仪验证

• 批准号: 2007670
• 负责人: Steven Abbott Johnson
• 金额: $ 29.31万
• 依托单位: TECHNISCAN, INC.
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-09-30 至 1998-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2007670
• 关键词: biomedical equipment development; breast neoplasm /cancer diagnosis; phantom model

The objective of this project is to demonstrate new, quantitative, ultrasound, imaging techniques for improve early breast cancer diagnosis. Computer simulations of the operation of a 3-D breast scanner and the actual scanning of test objects, tissue samples and a whole breast radical mastectomy sample in a laboratory mechanical rotational scanner will be done. A 1-D transmitting transducer array and a 1.5-D receiving transducer array will be used to collect data to form a 339 pixel diameter images of a 5 inch diameter circular cross section through the breast. These quantitative images of sound speed and absorption will have 0.75 mm spatial resolution. Effects of out of plane scattering will be minimized by the use of vertical transmitter and receiver focusing. Synthetic focus images of 677 pixel diameter, with spatial resolution of 0.28 mm will be made using a l.5-D, 4 MHz common transmitter/receiver transducer array. The path to explore a fully electronic scanned ring of transducers for rapid imaging of patients to remove motion artifacts will be provided by modifying a commercial clinical scanner connected to a small ring of 256 transducers operating at 2.25 MHz. PROPOSED COMMERCIAL APPLICATION: Our new generation of breast cancer scanners will provide images that are far superior to present commercial scanners. In addition to creating this new market, this work, these algorithms, and inverse scattering in particular, has applications in non medical areas: mine detection, buried waste imaging, sonar imaging, and non destructive testing (NDT).

该项目的目标是展示新的，定量的， 超声、影像学技术提高早期乳腺癌诊断。 三维乳腺扫描仪操作的计算机模拟和 对测试对象、组织样本和整个乳腺癌进行实际扫描 将在实验室机械旋转扫描仪中对乳房切除术样本进行 完了1-D发射换能器阵列和1.5-D接收换能器 阵列将用于收集数据，以形成339像素直径的图像， 5英寸直径的圆形横截面穿过乳房。这些 声速和吸收的定量图像将具有0.75 mm 空间分辨率面外散射的影响将被最小化 通过使用垂直发射器和接收器聚焦。合成聚焦 图像的677像素直径，空间分辨率为0.28毫米， 使用1.5-D、4 MHz公共发射器/接收器换能器阵列进行。 探索全电子扫描传感器环的途径， 将通过以下方式对患者进行快速成像以去除运动伪影： 修改连接到256个小环的商业临床扫描仪， 传感器工作频率为2.25 MHz。 拟议的商业应用：我们的新一代乳腺癌 扫描仪将提供远优于目前商业的上级图像 扫描仪除了创造这个新市场，这项工作，这些 算法，特别是逆散射，在非 医疗领域：地雷探测、掩埋废物成像、声纳成像，以及 无损检测（NDT）。