MULTIJOINT CONTROL FOR LOWER EXTREMITY NEUROPROSTHESES

描述（改编自申请人的摘要）： 长期 本研究的目标是开发电刺激系统， 为半身不遂和半身不遂患者提供家庭和工作场所的活动能力 患有脊髓损伤、中风或 头部受伤。 这项工作是针对发展 不需要大量矫形器的康复装置。 那里 需要改进运动控制，以便实现更好的运动控制。 平衡，更平稳，更节能的运动，可靠 完成爬楼梯和下降，和拐杖行走。 这 项目将解决关键控制问题，其解决方案是 神经假体实现这些目标所必需的。 底层 所提出的工作的科学假设是， 膝盖、脚踝和臀部可以通过反馈控制器来实现， 基于关节角度、足部端点的真实的时间测量 位置和足部接触力，调节 肌肉，因此，净力矩和机械阻抗， 每个关节，以获得所需的运动。 第二个假设是 有多组刺激波形可以达到相同的效果， 运动，并且每组中涉及的共刺激量是 与控制系统实现规定的 尽管有机械干扰。 第三个假设是， 共刺激的量与有效刺激的持续时间有关。 控制（例如，抗疲劳性）。 本项目将测试这些 假设通过开发和表征这样的性能 反馈控制器 具体目标是：（1）发展和 通过实验验证电刺激肌肉预测模型 反应 将为踝关节、膝关节和髋关节开发模型 （单独和组合），并将解释共刺激 激动剂肌肉电极，刺激脉冲频率的调制， 宽度、被动和外部机械负荷以及肌肉疲劳。 将电刺激和关节角度与生成的网络相关联的模型 关节力矩以及由此产生的主动刚度和阻尼 生物力学系统将被考虑; 2）开发和评估 调节电刺激的反馈控制器的能力， 实现关节角度和/或接触力的指定轨迹; 以及3）这些控制器中最好的将被应用于成就 改善截瘫患者的楼梯上升和下降， 电脑控制的电刺激

DESCRIPTION (Adapted from the Applicant's Abstract): The long-term goal of this research is to develop electrical stimulation systems that provide home and workplace mobility to paraplegic and hemiplegic patients having paralysis arising from spinal cord injury, stroke or head injury. This work is directed toward the development of rehabilitative devices that do not require substantial orthoses. There is a need for improved control of motion, so as to achieve better balance, smoother and more energy efficient locomotion, reliable accomplishment of stair climbing and descent, and crutch walking. This project will addresses critical control problems whose solution is necessary for neuroprostheses to attain these goals. The underlying scientific hypothesis of the proposed work is that specified motions of the knee, ankle and hip can be achieved by feedback controllers which, on the basis of real time measurements of joint angles, foot endpoint position and foot contact forces, modulate the co-stimulation of muscles, and consequently the net moments and mechanical impedances at each joint, so as to obtain the desired motion. A second hypothesis is that there are multiple sets of stimulus waveforms that achieve the same motion, and that the amount of co-stimulation involved in each set is related to the ability of the control system to achieve the prescribed trajectory despite mechanical disturbances. A third hypothesis is that the amount of co-stimulation is related to the duration of effective control (e.g., the fatigue resistance). This project will test these hypotheses by developing and characterizing the performance of such feedback controllers. Specific Aims are: 1) to develop and experimentally verify predictive models of electrically-stimulated muscle response. Models will be developed for the ankle, knee and hip joints (separately and in combination), and will account for co-stimulation of agonist muscle electrodes, modulation of stimulus pulse frequency and width, passive and external mechanical loads, and muscle fatigue. Models relating electrical stimulation and joint angles to generated net joint moments and the active stiffness and damping of the resulting biomechanical systems will be considered; 2) to develop and evaluate the ability of feedback controllers that modulate electrical stimulation to achieve specified trajectories of joint angles and/or contact forces; and 3) the best of these controllers will be applied to the achievement of improved stair ascent and descent by paraplegic patients, through computer-controlled electrical stimulation.