SOCIOECONOMIC STATUS AND MELANOMA SURVIVAL

社会经济状况和黑色素瘤生存率

• 批准号: 2105387
• 负责人: DONALD R MILLER
• 金额: $ 8.15万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-04-01 至 1995-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2105387
• 关键词: cancer risk; human mortality; interview; melanoma; neoplasm /cancer classification /staging; neoplasm /cancer diagnosis; neoplasm /cancer epidemiology; self care; socioeconomics

Melanoma is an increasingly common, and often fatal form of skin cancer for which the substantial prognostic advantages of early detection and treatment. Preliminary evidence suggests that people of low socioeconomic status may have particularly poor survival from melanoma, perhaps because there is a tendency for the cancer to be detected and treated at a more advanced stage in these people. We propose to study the relationship of socioeconomic status to melanoma detection, survival and mortality in a recent case-control study in Connecticut. This is a rich, unique data set for such analyses, because the study is population-based with rapid case ascertainment, includes a comprehensive assessment of risk factors as well as self-screening, health care use, and other factors related to detection of melanoma, and it has on-going follow-up of cases for vital status and recurrence of the cancer. With assignment of socioeconomic status based on education, occupation, and composite indices, we will determine whether cases of lower socioeconomic status have more late stage melanoma or thicker lesions at diagnosis and whether they have more recurrence of the cancer or poorer survival compared to cases of higher socioeconomic status. Subsequently, we will evaluate the extent to which such differences are related to patients' behavioral, medical, and other characteristics, including knowledge of melanoma, frequency of skin self- examinations or examinations by medical personnel, or access to and use of health care services. This research directly addresses several of the high priority research needs for cancer control science in Health People 2000. The results will have important implications for detection and control of cutaneous melanoma, and should help shape future efforts to limit melanoma mortality.

黑色素瘤是一种越来越常见的，往往致命的皮肤癌 因此，早期发现和 治疗初步证据表明，低社会经济地位的人 黑色素瘤患者的生存率可能特别低，这可能是因为 癌症的检测和治疗有一种趋势， 在这些人中的高级阶段。我们建议研究 社会经济状况与黑色素瘤检测、生存率和死亡率的关系 最近在康涅狄格州的病例对照研究。这是一个丰富独特的数据集 对于此类分析，因为研究是基于人群的， 确定，包括风险因素的全面评估，以及 作为自我筛查、医疗保健使用和其他相关检测因素 黑色素瘤，它有正在进行的后续行动的情况下， 癌症复发。 根据社会经济地位分配 在教育、职业和综合指数方面，我们将确定 社会经济地位较低的病例有更多的晚期黑色素瘤， 诊断时较厚的病变以及是否有更多的复发 与较高社会经济地位的病例相比， status.随后，我们将评估这种 差异与患者的行为，医疗和其他有关 特征，包括黑色素瘤的知识，皮肤自身的频率， 检查或由医务人员检查，或获得和使用 医疗保健服务。这项研究直接解决了几个高 《2000年健康人》中癌症控制科学的优先研究需求。 这些结果将对检测和控制 皮肤黑色素瘤，并应有助于塑造未来的努力，以限制黑色素瘤 mortality.