LONG TERM HEALTH IMPACT OF BODY WEIGHT CHANGE

最近的证据表明，可能有长期的不利健康 与体重波动相关的影响，但还需要进一步研究。 这一试点项目的目的是开发和评估 成年男性体重变化和变异性的测量 弗雷明翰心脏研究队列和弗雷明翰研究中的女性 子女/配偶队列。这包括评估一个简单的权重 在两个考试周期中进行历史问卷调查 子女/配偶队列，普遍体重病史模式的描述 在这两个队列中，并开发了一种更全面的新工具 体重历史评估，包括意图、方法、 时间和重量变化的程度。所获得的措施将用于 分析了权重变化的关系决定因素以及 预期会有多种健康后果。此外，新推出的 开发的评估体重历史的工具将应用于 在下一个面试周期，弗雷明翰队列，并可能被管理 在其他大型队列中也是如此，为未来的分析提供了数据。这个 提出项目将为健康研究做出重要贡献 美国成年人体重变化模式的影响。

Recent evidence has suggested that there may be long-term adverse health effects associated with weight fluctuations but further research is needed. The aim of this pilot project is to develop and evaluate methodology for the measurement of change and variability in body weight among adult men and women in the Framingham Heart Study Cohort and the Framingham Offspring/Spouse Cohort. This includes evaluation of a brief weight history questionnaire administered in two examination cycles of the Offspring/Spouse Cohort, description of prevalent weight history patterns in both cohorts, and development of a new instrument for more comprehensive assessment of weight history, including details on intention, means, timing, and extent of weight change. Measures obtained will be used in analyses examining the relations determinants of weight change as well as prospectively with a variety of health outcomes. In addition, the newly developed instrument for assessing weight history will be administered to the Framingham cohorts at the next interview cycle, and may be administered in other large cohorts as well, providing data for future analyses. The propose project will make important contributions to the study of health effects of weight change patterns among adult Americans.