RETINAL ARTERY READING CENTER

视网膜动脉读数中心

• 批准号: 2313556
• 负责人: MATTHEW D DAVIS
• 金额: $ 4.49万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-11-09 至 1996-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2313556
• 关键词: RETINAL; ARTERY; READING; CENTER

The purpose of this contract is to provide the services of a reading center to interpret photographs from approximately 14,500 retinal examinations (including a small percentage of blind replicate photographs), performed in the epidemiological research study of the major factors contributing to the occurrence and trends of cardiovascular disease in middle-aged adults entitled "Atherosclerosis Risk in Communities Study (ARIC)". The Retinal Artery Reading Center will assist in protocol development for the performance of retinal artery examinations in the four ARIC Field Centers, and will perform measurements and interpretations of these images in a standardized and reproducible manner. The primary objective of the Retinal Artery Reading Center is to develop, implement, and monitor performance of a protocol for the retinal photography examinations within the Atherosclerosis Risk in Communities Study. The objectives of this additional component are: 1. To assess and quantitate the independent relationship between retinal arteriosclerosis and incident CVD events. 2. To examine differences between the CVD risk factor and event profiles of retinal arteriosclerosis and carotid atherosclerosis. 3. To determine the association between retinal arteriosclerosis and cerebral MRI findings, including infarct-like lesions and small white matter lesions. 4. To contrast the profiles of cerebral MRI findings associated with retinal arteriosclerosis and carotid atherosclerosis. 5. To assess the relationship between retinal arteriosclerosis and cognitive decline.

本合同的目的是提供阅读服务 中心可解读约 14,500 个视网膜的照片 检查（包括一小部分盲重复 照片），在流行病学研究中进行 心血管疾病发生及趋势的主要因素 中年人疾病题为“动脉粥样硬化风险” 社区研究（ARIC）”。视网膜动脉读数中心将协助 视网膜动脉性能的方案开发 在四个 ARIC 现场中心进行考试，并将进行 以标准化和标准化的方式对这些图像进行测量和解释 可重复的方式。 视网膜动脉读数中心的主要目标是开发、 实施并监测视网膜协议的性能 社区动脉粥样硬化风险的摄影检查 学习。 该附加组件的目标是： 1. 评估和定量视网膜之间的独立关系 动脉硬化和心血管疾病事件。 2. 检查 CVD 危险因素和事件概况之间的差异 视网膜动脉粥样硬化和颈动脉粥样硬化。 3. 确定视网膜动脉硬化与视网膜动脉硬化之间的关系 脑 MRI 结果，包括梗塞样病变和小白斑 物质病变。 4. 对比与以下相关的脑 MRI 结果的概况 视网膜动脉粥样硬化和颈动脉粥样硬化。 5. 评估视网膜动脉硬化与视网膜动脉硬化之间的关系 认知能力下降。