RETINAL ARTERY READING CENTER FOR THE ARIC STUDY

本合同的目的是提供阅读服务 该中心解释了大约14，500张视网膜照片 检查（包括小部分盲法重复检查） 照片），在流行病学研究中进行， 心血管疾病发生和发展趋势的主要因素 一项名为“中年人动脉粥样硬化风险”的研究， 社区研究（ARIC）。 视网膜动脉阅读中心将协助 在视网膜动脉性能的方案开发中 在四个ARIC现场中心的考试，并将执行 测量和解释这些图像在一个标准化的， 可复制的方式。 视网膜动脉阅读中心的主要目标是开发， 实施和监控用于视网膜的协议的性能 社区动脉粥样硬化风险中的摄影检查 Study. 这一新增部分的目标是： 1.评估和定量视网膜病变与视网膜病变之间的独立关系， 动脉硬化和意外CVD事件。 2.检查CVD风险因素和事件特征之间的差异 视网膜动脉硬化和颈动脉粥样硬化。 3.为了确定视网膜动脉硬化和 脑部MRI表现，包括梗死样病变和小白色 物质损伤 4.对比与脑梗死相关的脑MRI表现， 视网膜动脉硬化和颈动脉粥样硬化。 5.评估视网膜动脉硬化与视网膜病变的关系， 认知能力下降

The purpose of this contract is to provide the services of a reading center to interpret photographs from approximately 14,500 retinal examinations (including a small percentage of blind replicate photographs), performed in the epidemiological research study of the major factors contributing to the occurrence and trends of cardiovascular disease in middle-aged adults entitled "Atherosclerosis Risk in Communities Study (ARIC)". The Retinal Artery Reading Center will assist in protocol development for the performance of retinal artery examinations in the four ARIC Field Centers, and will perform measurements and interpretations of these images in a standardized and reproducible manner. The primary objective of the Retinal Artery Reading Center is to develop, implement, and monitor performance of a protocol for the retinal photography examinations within the Atherosclerosis Risk in Communities Study. The objectives of this additional component are: 1. To assess and quantitate the independent relationship between retinal arteriosclerosis and incident CVD events. 2. To examine differences between the CVD risk factor and event profiles of retinal arteriosclerosis and carotid atherosclerosis. 3. To determine the association between retinal arteriosclerosis and cerebral MRI findings, including infarct-like lesions and small white matter lesions. 4. To contrast the profiles of cerebral MRI findings associated with retinal arteriosclerosis and carotid atherosclerosis. 5. To assess the relationship between retinal arteriosclerosis and cognitive decline.