Non-invasive safe electrical stimulation using AI to save lives

在持续的COVID-19大流行期间，压力和心理健康问题席卷全球。人们越来越意识到，在我们的社会中管理心理健康至关重要。虽然各种药物和天然/替代解决方案为我们的心理健康提供了一些支持，但这些药物几乎无法控制，并且可能会产生严重的副作用。自然疗法最多只能起到适度的效果。如果我们能够通过触摸按钮来控制您的心理健康，甚至通过对关键人员的心理健康和健康进行仔细的个性化监测和管理来挽救生命，那不是很好吗？在BrainPatch，我们是一个由科学家和经验丰富的企业家组成的团队，由世界一流的专家顾问提供支持。我们的目标是为一系列应用开发安全有效的脑刺激平台技术。我们最初提出使用非侵入性迷走神经刺激来调节重症Covid-19患者的免疫系统。虽然这被证明对自身免疫性疾病和类风湿性关节炎患者的侵入性迷走神经刺激有效，但它没有在Covid-19患者中进行测试，我们遇到医生不愿意在他们的重症Covid-19患者中测试我们的方法，特别是因为地塞米松已经发展成为一种可靠和经过测试的标准护理，用于调节免疫反应。因此，考虑到这一点，也考虑到与大流行病有关的新出现的心理健康危机，我们提议改变项目范围。我们建议重新使用我们在项目开始时生成的设备，算法和协议的部分内容，以应对大多数人口中出现的压力和精神疲劳的增加。该项目旨在使公司更接近于将该解决方案交付给希望拥有个性化应用程序以科普压力的人们。该项目还为进一步研究奠定了基础，旨在将这项技术交给照顾有心理健康问题的患者或患有慢性疲劳和炎症综合征的医生。

Stress and mental health issues have taken the world over by storm during the ongoing COVID-19 pandemic. There is a growing awareness that managing mental wellbeing in our society is critical. While a variety of pharmaceutical and natural/alternative solutions provide some support for our mental health, the medicines give you very little control and can have severe side effects. The natural remedies are modestly effective at best. Wouldn’t it be great if we could control your mental wellbeing at the touch of a button and even potentially save lives by careful personalised monitoring and management of mental health and wellbeing in key personnel? At BrainPatch we are a team of scientists and experienced entrepreneurs backed by world-class expert advisors. Our aim is to develop a platform technology of safe and effective brain stimulation for a range of applications. We have originally proposed to use non-invasive vagus nerve stimulation to regulate the immune system in critically ill Covid-19 patients. While this was shown to be effective with invasive vagus nerve stimulation in patients with autoimmune disorders and rheumatoid arthritis, it was not tested in Covid-19 patients and we came across a reluctance from doctors to test our approach with their critically ill Covid-19 patients especially as dexamethasone has evolved as a reliable and tested standard of care for the purpose of regulating immune response. So, taking this into consideration and also considering the emerging mental health crisis related to the pandemic we are proposing a change of the project scope. We propose to re-use the equipment, algorithms and parts of the protocol we generated at the start of the project for the purpose of dealing with a rise in stress and mental fatigue seen in the majority of the population. This project aims to bring the company closer to putting this solution in the hands of people, who would want to have a personalised app to cope with stress. This project also lays the ground for further research aimed at putting this technology in the hands of the doctors taking care of patients with mental health issues or those suffering from syndrome of chronic fatigue and inflammation in “long-Covid”.