THREE DIMENSIONAL CT ANGIOGRAPHY

描述（改编自申请人的摘要）：计算机断层扫描 (CT)血管造影术是一种用于对血管系统进行成像的方法， 结合创新的图像处理与使用新的滑环CT 扫描仪 该方法允许快速获取大的 在外周动脉相期间的CT数据的体积 静脉注射造影剂 拟议项目的目标 就是开发利用这一点的算法和技术 容积扫描CT技术，用于生成三维CT血管造影片 可以替代更昂贵和侵入性的动脉内 血管造影在腹部内的特定应用。 技术 发展将包括计算机算法的生产两个 来自3-D CT数据的三维（2-D）血管造影片，造影剂团注时间 技术，最大限度地减少运动和推注定时的伪影 不准确性，以及分割的图像处理策略 包含骨骼和软组织的复杂血管结构 组织. 将进行临床研究，以评估诊断 该方法在肾动脉狭窄和腹部狭窄中的准确性 主动脉瘤 在该项目顺利完成后， 申请人预计，该方法将是一个较低的成本， 诊断性动脉造影的风险替代品。

DESCRIPTION (Adapted from Applicant's Abstract): Computed Tomography (CT) Angiography is a method for imaging the vascular system that combines innovative image processing with the use of new slip-ring CT scanners. This method allows for the rapid acquisition of large volumes of CT data during the arterial phase of a peripheral intravenous contrast injection. The goals of the proposed project would be to develop the algorithms and techniques that exploit this volume-scan CT technology to produce three-dimensional CT angiograms that could substitute for more costly and invasive intra-arterial angiograms in specific applications within the abdomen. The technical developments would include computer algorithms for production of two dimensional (2-D) angiograms from 3-D CT data, contrast bolus timing techniques, minimization of artifacts from motion and bolus timing inaccuracies, and image processing strategies for segmentation of complex vascular structures from volumes containing bones and soft tissue. Clinical studies would be conducted to assess the diagnostic accuracy of the method in renal artery stenosis and in abdominal aortic aneurysms. Upon the successful completion of this project, the applicants projected that the method would be a lower cost, lower risk alternative to diagnostic arteriography.