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Cellblocks - novel cell culture device

Cellblocks - 新型细胞培养装置

基本信息

批准号：
700596
负责人：
金额：
$ 3.07万
依托单位：
REVIVOCELL LIMITED
依托单位国家：
英国
项目类别：
GRD Proof of Market
财政年份：
2015
资助国家：
英国
起止时间：
2015 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=700596
关键词：
Cellblocks novel cell culture device

项目摘要

Cell culture is a process whereby living cells are grown in laboratory conditions for variousscientific experiments, without using animals, for example: to gain better understanding ofbodily function, disease processes or to develop new drugs. Traditionally, cells have beengrown in hard and flat 2-D (two-dimensional) surfaces, either in glass or plastic, and thistechnology has not changed significantly since the invention of the Petri dish by JuliusRichard Petri in 1870s. Researchers across many sectors, including pharmaceutical industry,research organisations and universities primarily apply conventional cell culture for thegrowth of mammalian cells, bacteria or viruses. Cell culture has played a vital role in manyLife Science discoveries such as the development of new drugs or vaccines. However, theresults often lack applicability as the cell growth is constrained within the available 2-Dsurface when compared to the real-world 3-D environment of living tissue. Revivocell Ltd hasbegun to develop a novel device for the growth of cell cultures in 3-D forms, under laboratoryconditions; these can mimic the function of living tissue much more closely. This technologywould potentially increase the success rate of developing new treatments and reduce thereliance on animal testing. The objective of this application is to assess the market potential ofour newly-developed patent pending device. Revivocell’s invention will provide a reliable,fast and cost-effective device that could be used worldwide in Life Sciences laboratories witha potential to become a standard method.

细胞培养是在实验室条件下培养活细胞，用于各种科学实验，而不使用动物，例如，为了更好地了解身体功能、疾病过程或开发新药。传统上，细胞生长在坚硬和平坦的二维(二维)表面上，无论是在玻璃还是塑料中，自从19世纪70年代Julius Richard Petri发明培养皿以来，这种技术没有明显的变化。许多部门的研究人员，包括制药业、研究机构和大学，主要应用传统的细胞培养来生长哺乳动物细胞、细菌或病毒。细胞培养在许多生命科学发现中发挥了至关重要的作用，如新药或疫苗的开发。然而，与活体组织的真实三维环境相比，这些结果往往缺乏适用性，因为细胞生长被限制在可用的二维表面内。Revivocell有限公司已经开始开发一种新的设备，用于在实验室条件下以3D形式生长细胞培养物；这些设备可以更接近地模拟活组织的功能。这项技术可能会提高开发新疗法的成功率，并减少对动物试验的依赖。这项申请的目的是评估我们新开发的专利申请设备的市场潜力。Revivocell的发明将提供一种可靠、快速和成本效益高的设备，可以在世界各地的生命科学实验室中使用，有可能成为标准方法。