CASANOVA, A GENE CONTROLLING SEX-SPECIFIC BEHAVIOR

这项研究计划的目标是分子分离和 一个新的基因命名为卡萨诺瓦（cas），这涉及到表征 与果蝇性别特异性行为的调节有关。进一步 CAS表型的表征将决定 涉及异常。P-元件诱变将用于产生 删除cas基因或新的等位基因。新的删除将 用于进一步将cas基因的位置定位到尽可能小的 地区特征噬菌体和粘粒克隆，位于区域内 将相对于它们在删除时的位置进行排序和放置 线识别转录单位的限制性片段， 放置在最小的包含CAS的区域内， cDNA克隆的分离。

The goal of this research proposal is the molecular isolation and characterization of a novel gene named Casanova (cas),which is involved with the regulation of sex-specific behavior in Drosophila. Further characterization of the cas phenotype will determine the type behavioral abnormalities involved. P-element mutagenesis will be used to create deletions removing the cas gene or new alleles. New deletions will be used to further map the position of the cas gene to the smallest possible region. Characterized phage and cosmid clones, located within the region will be ordered and placed relative to their position on the deletion lines. Restriction fragments which identify transcription units and are placed within the smallest cas containing region will be used for the isolation of cDNA clones.