TONGUE/JAW LINKAGES IN FEEDING

喂食时的舌头/下巴连接

• 批准号: 2414651
• 负责人: Jeffrey Bruce Palmer
• 金额: $ 18.07万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-05-01 至 1999-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2414651
• 关键词: barium; brain regulatory center; cinefluorography; clinical research; computer program /software; digital imaging; eating; gastrointestinal imaging /visualization; human subject; image processing; jaw movement; mastication; neuroregulation; palate; swallowing; tongue; videotape /videodisc

The purpose of this study is to describe the motions of the tongue and jaw during feeding. Prior studies of mastication in man have focused on the motions of the teeth and jaws, but the role of the tongue in food transport and positioning and the oral stage of swallowing have been neglected. Motions of the jaw, tongue, and palate have characteristic patterns in macaque and lower mammals, which vary with the consistency of the food. Our preliminary studies show similar patterns in man. We will expand our current studies by determining the spatial and temporal relationships between tongue and jaw motion cycles, and how these motions are influenced by the initial food consistency and stage in sequence (from ingestion to terminal swallow). We will use videofluorography in the lateral and postero-anterior projections to study forty normal subjects eating soft and hard solid foods. Small radiopaque markers will be glued to the surface of the tongue to demonstrate its motions. Twenty subjects will have midline tongue markers and twenty will have triangulated markers. For half the subjects in each group, food will be combined with barium to reveal its movement relative to oral and pharyngeal structures. The progression of the bolus through the foodway and the overall movement patterns of the jaw, hyoid bone, and tongue will be evaluated by reviewing the videotapes in slow motion. Selected sequences will be digitized with image processing software and the Cartesian coordinates for the jaw, hyoid bone, and tongue, jaw reference points established. Computer graphics will be used to display motion of these structures over time. Data analysis will establish the spatial and temporal relationships of the jaw, tongue, and hyoid bone, and how these are influenced by both initial food consistency and stage (from ingestion to terminal swallow). Movements of the tongue in the coronal plane will be analyzed as a measure of tongue rotation during chewing. Descriptive and analytical statistics will be used to develop a multivariate model for tongue-jaw behavior and to examine current models for neural control of mastication and swallowing. This knowledge is essential to understanding the motor control for mastication and swallowing and will ultimately lead to progress in the evaluation and treatment of dysphagic individuals.

本研究的目的是描述舌头和下颌的运动 在喂食期间。先前对人类咀嚼的研究主要集中在 牙齿和颌骨的运动，但舌头在食物中的作用 运输和定位以及吞咽的口腔阶段， 忽视下颌、舌头和上颚的运动具有特征性 猕猴和低等哺乳动物的模式，这与一致性的变化， 食物我们的初步研究显示人类也有类似的模式。我们会 通过确定空间和时间来扩展我们目前的研究 舌头和下巴运动周期之间的关系，以及这些运动 受初始食物稠度和顺序阶段的影响（从 吞咽至最终吞咽）。 我们将在侧位和后前位使用视频荧光造影术 研究了40名正常受试者吃软固体和硬固体 食品小的不透射线标记将被粘在舌头表面 来演示它的动作20名受试者将有中线舌 20个将具有三角形标记。一半的实验对象 在每组中，食物将与钡结合以显示其运动 相对于口腔和咽部结构。大剂量的进展 以及下颌、舌骨和下颌骨的整体运动模式 骨和舌头将通过缓慢的录像带进行评估。 议案所选序列将通过图像处理进行数字化 软件和下颌、舌骨和下颌的笛卡尔坐标， 建立了舌颌参考点将使用计算机图形 来显示这些结构随时间的运动。数据分析将 建立下颌、舌头和 舌骨，以及这些是如何受到影响， 和阶段（从摄入到最终吞咽）。舌头的运动 冠状面将被分析作为舌旋转的测量， 咀嚼。描述性和分析性统计将用于制定 多变量模型的舌颌行为，并检查当前的模型 用于咀嚼和吞咽的神经控制这种知识是 对于理解咀嚼的运动控制至关重要， 吞咽，并最终导致评估的进展， 治疗吞咽困难的患者。