RESILIENCE & QUALITY OF LIFE IN ADOLESCENTS WITH CANCER

弹力

• 批准号: 2519824
• 负责人: JOAN Ellen HAASE
• 金额: $ 7.53万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-01 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2519824
• 关键词: adolescence (12-20); behavioral /social science research tag; child (0-11); clinical research; family structure /dynamics; human subject; human therapy evaluation; longitudinal human study; pediatric neoplasm /cancer; psychological adaptation; psychological aspect of cancer; psychological models; psychometrics; quality of life; self concept; social psychology; social support network

DESCRIPTION: (Adapted from investigator's abstract) Statistics for childhood cancer demonstrate greatly improved survival rates over the last twenty years in the United States. Depending on the type of cancer, 58-88% of children and adolescents will be long-term, disease free survivors. While such statistics are encouraging, the nature and course of many cancers has changed from an inevitably fatal illness to a chronic illness that continues to carry the potential to threaten life. The American Cancer Society had identified adolescent cancer care, including psychosocial care, as a research priority. Yet, surprisingly few data-based studies have been reported on psychosocial adjustment of adolescents with cancer (AWC). In addition, systematically planned psychosocial intervention studies with AWC are rare, even though such interventions, tested over the last 2 decades in adults with cancer, show promising results. With over 200,000 childhood cancer survivors and the numbers projected to be 1 in 250 by the year 2000, it is imperative that adjustment issues for adolescents with cancer be addressed. The purposes of this study are to: 1) examine, longitudinally, the nature and patterns of change in resilience and quality of life through analysis of the Adolescent Resilience Model (ARM) in adolescents with cancer; and, 2) evaluate the extent to which patterns of resilience and quality of life change as a result of a family and adolescent network (FAN) intervention aimed at enhancing resilience and quality of life through individual, family and social protective factors in the ARM. The study design contains two components. To answer questions about relationships and causality among individual, family and social protective factors, illness-related and individual risk factors, and resilience and quality of life among adolescents with cancer, 11-19 year of age, a prospective longitudinal descriptive design will be used. The adolescents will be followed from diagnosis through the first of living with cancer. In the last 2 1/2 years of the project, after refinement and pilot work is done on the FAN intervention, a longitudinal experimental design w ill be implemented to evaluate changes that occur in the factors in the ARM as a result of a Family and Adolescent Network (FAN) intervention that is targeted to enhance individual, family, and social protective factors in the model and minimize illness- related and individual risk factors. The proposed total sample size is 243. Analysis of study aims will be accomplished through: 1) growth curve analysis to evaluate initial state, rate of change and stability; 2) common factor modeling of growth curve parameters; and 3) structural modeling of change factors over time and as a result of the intervention.

描述：（改编自研究者摘要） 儿童癌症的存活率比过去大大提高， 二十年在美国。 根据癌症的类型，58-88% 儿童和青少年将成为长期的无病幸存者。 虽然这些统计数字令人鼓舞，但许多癌症的性质和病程 已经从一种不可避免的致命疾病变成了一种慢性疾病， 仍然有可能威胁生命 美国癌症 社会已经确定了青少年癌症护理，包括心理社会护理， 作为研究重点。 然而，令人惊讶的是， 报告了青少年癌症（AWC）的心理社会调整。 在 此外，系统计划的AWC心理社会干预研究 是罕见的，即使这样的干预措施，在过去的20年里， 患有癌症的成年人显示出有希望的结果。 有超过20万的儿童 到2000年，癌症幸存者的人数预计为250人中有1人， 对于患有癌症的青少年来说， 处理。 本研究的目的是：1）纵向考察， 复原力和生活质量变化的性质和模式， 青少年心理弹性模型（ARM）分析 癌症;以及，2）评估弹性模式和 家庭和青少年网络（FAN）导致生活质量的变化 旨在通过以下措施提高复原力和生活质量的干预措施： 个人、家庭和社会保护因素的研究 设计包含两个部分。 来回答关于人际关系的问题， 个人、家庭和社会保护因素之间的因果关系， 与疾病有关的风险因素和个人风险因素，以及 11-19岁青少年癌症患者生活的前瞻性研究 采用纵向描述性设计。 青少年将 从确诊到第一次患癌。 在 项目的最后2 1/2年，经过完善和试点工作， FAN干预，纵向实验设计将 实施，以评估ARM中的因素发生的变化， 家庭和青少年网络（FAN）干预的结果， 有针对性地加强个人、家庭和社会保护因素， 建立模型并最大限度地减少与疾病相关的和个人的风险因素。 的 建议的样本总数为243个。 研究目的分析将 通过：1）生长曲线分析以评估初始状态， 增长曲线的公因子建模 参数;以及3）随时间变化的变化因素的结构建模， 干预的结果。