EASTERN COOPERATIVE ONCOLOGY GROUP

此拨款申请的目的是支持马约诊所 东部肿瘤协作组（ECOG）。 的目标 旨在更好地了解癌症， 了解癌症相关问题，改善癌症的发展 治疗方案，提高癌症患者的生存率。 马约诊所 在明尼苏达州的罗切斯特、佛罗里达的杰克逊维尔和 斯科茨代尔，亚利桑那州，有资源，人员，设施， 患者人群，以促进对研究的强大贡献 ECOG方案。 随着马约的不断成长和发展 医疗实践和继续北中央癌症治疗小组 （NCCTG）活动，我们预计会有大量的方案进入， 科学贡献。 这种ECOG隶属关系和治疗方案 已经发展为马约诊所提供了主要的好处， 研究人员，区域癌症计划，以及癌症的大群体， 参与这些研究活动的患者。 具体 本赠款提案的目的是支持马约的以下方面 临床ECOG研究活动包括： 1. 全组ECOG癌症治疗方案的患者招募 2. 新方案设计和治疗方案的评价， 提供背景临床数据，以证明全组ECOG II期的合理性， III癌症治疗方案 3. 协调和参与基于实验室的 与ECOG癌症治疗方案相关的研究 4. 参与针对特定疾病的活动， 可以指定和适当的角色。

The purpose of this grant application is to support Mayo Clinic membership in the Eastern Cooperative Oncology Group (ECOG). The goals are directed toward a greater understanding of cancer, a better understanding of cancer-related problems, development of improved cancer treatment programs, and improved cancer-patient survival. Mayo Clinic at its three campuses in Rochester, Minnesota, Jacksonville, Florida, and Scottsdale, Arizona, has the resources, personnel, facilities, and patient population to facilitate strong contributions to the research programs of ECOG. With the continued growth and development of the Mayo medical practice and continuing North Central Cancer Treatment Group (NCCTG) activities, we would anticipate significant protocol entry and scientific contribution. This ECOG affiliation and treatment programs which have evolved provide major benefits to Mayo Clinic, its investigators, regional cancer programs, and the large group of cancer patients who are involved in these research activities. The specific aims of this grant proposal are to support the following aspects of Mayo Clinic ECOG research activities including: 1. Patient accrual to group-wide ECOG cancer treatment protocols 2. The evaluation of new protocol design and treatment regimens to provide background clinical data to justify group wide ECOG Phase II and III cancer treatment protocols 3. Coordination of and participation in adjunctive laboratory-based correlative studies in association with ECOG cancer treatment protocols 4. Participation in disease-specific activities and such administrative roles as might be appointed and appropriate.