DEV MACHINE MEASURE MECHANICAL PROPERTIES--RODENT BONES

开发机测量机械特性——啮齿动物骨骼

• 批准号: 2649694
• 负责人: Guigen Zhang
• 金额: $ 9.95万
• 依托单位: GZ TECHNOLOGIES
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-22 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/2649694
• 关键词: Rodentias; biomarker; biomedical equipment development; bone; measurement; mechanical stress; method development; physical property; tensile strength

GZ Technologies proposes to develop a compact size, high precision, low- cost, multifunctional, and easy-to-use miniature machine for measuring mechanical properties and other stress or strain markers of rodent long bones and vertebrae for the purpose of promoting the development of compounds to combat osteoporosis. The multifunctional feature of this machine will allow its application in rodent bone testing using compression, tension, bending and torsion methods. It is also applicable to low-load mechanical measurement in the fields of mechanical engineering, materials science, and biomedical engineering. This miniature mechanical machine will use latest technologies such as high precision and program-controllable linear DC step motor for actuation, and computer aided controlling, monitoring and data acquisition. The main goal of the proposed Phase I effort will be to demonstrate the feasibility of the novel design, and to test the ability of using single motor actuation for multifunction usage. The goal will be achieved by the fabrication of a prototype of the proposed design and the demonstration of its full functionality. The results of Phase I effort will set the stage for the creation of the proposed machine with multifunctional, low-cost, high precision, and easy-to-use features during Phase II. The Phase I effort will certainly be of great value to future R & D activities towards biomedical engineering application.

GZ Technologies 提议开发一种尺寸紧凑、高精度、低功耗的 成本低、多功能且易于使用的微型测量机器 啮齿动物长的机械性能和其他应力或应变标记 骨骼和椎骨，以促进发育 对抗骨质疏松症的化合物。这款产品的多功能特点 机器将允许其在啮齿动物骨骼测试中的应用 压缩、拉伸、弯曲和扭转方法。也是适用的 机械领域的低负载机械测量 工程学、材料科学和生物医学工程。这个微型 机械设备将采用最新技术，如高精度和 用于驱动的​​程控线性直流步进电机和计算机 辅助控制、监测和数据采集。该组织的主要目标是 拟议的第一阶段工作将是证明该计划的可行性 新颖的设计，并测试使用单电机驱动的能力 多功能使用。该目标将通过制造 拟议设计的原型及其完整的演示 功能。第一阶段工作的结果将为 创建具有多功能、低成本、高性价比的拟议机器 第二阶段的精度和易于使用的功能。第一阶段的努力 对于未来的研发活动肯定具有巨大的价值 生物医学工程应用。