COMPUTER AIDED CARDIOPULMONARY SLEEP STUDIES

计算机辅助心肺睡眠研究

• 批准号: 2037974
• 负责人: JACK R. SMITH
• 金额: $ 35.31万
• 依托单位: NEUROTRONICS, INC.
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-08-08 至 1999-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2037974
• 关键词: arousal; cardiovascular function; clinical research; computer program /software; computer system design /evaluation; electroencephalography; electromyography; human subject; oximetry; respiratory function; sleep disorders

This proposal is concerned with the development of a computer system to aid cardio-pulmonary sleep studies. The research will lead to the design and development of a system which objectively detects and quantifies phasic events in multiple channel polysomnography studies. The research will develop objective definitions and measurements standards for phasic events including microarousals, microsleep, apneas, hypoxemic events, and leg myoclonus. Relationships between these events and phasic events in the EEG, EOG, and EMG data will be studied. The feasibility of the approach was established in the Phase I research by deriving methods for detecting microsleep and micro- arousals. The methodology will be used by the Henry Ford Sleep Disorder Center to quantify the fragmentation of sleep as characterized by microarousals in the EEG in association with morbidity characterized by daytime hypersomnolence. The Henry Ford Sleep Disorder Center will provide the all-night sleep recordings with sixteen channels of polysomnography stored on computer disk. The recordings will be from patients with apnea, period leg movements, and disturbed nocturnal sleep and will be hand-scored for sleep stages and transient arousals. The research will also evaluate the validity of polysomnography scoring from a computer screen.

这项建议是关于发展一个电脑系统 来帮助心肺睡眠研究 这项研究将导致 设计和开发一个系统， 量化多通道多导睡眠描记研究中的阶段性事件。 这项研究将制定客观的定义和衡量标准 包括微觉醒、微睡眠、呼吸暂停 低氧血症和腿部肌阵挛 这些之间的关系 EEG、EOG和EMG数据中的事件和阶段性事件将被 研究了 该方法的可行性已在第一阶段确定 通过推导出检测微睡眠和微睡眠的方法， 唤醒 该方法将用于亨利福特睡眠 疾病中心量化睡眠的碎片， 通过EEG中的微觉醒与特征为 白天过度嗜睡 亨利福特睡眠障碍中心将 提供16个通道的整夜睡眠记录， 存储在电脑磁盘上的多导睡眠图。 录音将来自 呼吸暂停、周期性腿部运动和夜间睡眠障碍患者 睡眠，并将对睡眠阶段和短暂觉醒进行手动评分。 本研究还将评估多导睡眠图评分的有效性 从电脑屏幕上。