CANCER EPIDEMIOLOGY AND BIOSTATISTICS

这项正在进行的杰出调查员补助金(OIG)的持续目标 是开发和使用生物统计学、生物数学和 旨在减少癌症发生的流行病学方法。这个 研究的目标有两个：第一，开发新的方法来研究 进行与癌症病因学有关的流行病学研究 可修改的个人特征，第二，使用这些方法 收集和分析与场地有关的该等特征的数据- 具体的癌症发生。无论是统计学还是流行病学 在过去的四年里，工作的重点是癌症 结直肠、卵巢、乳腺和前列腺。最重要的研究 取得的成就是#年中国人结直肠癌的研究 美国、加拿大和中国在饮食、体力活动和 体型，对12个美国病例的原始数据进行了合作分析-- 卵巢癌的对照研究和前列腺癌的三项研究 癌症。这部作品在几篇社论中都有特色。 科学期刊。未来的计划是解决统计问题 以及在癌症研究中出现的流行病学问题 前列腺和卵巢。方法论和流行病学研究 努力的重点将是更好地了解 遗传易感性与可改变的生活方式特征 这些癌症的病因。

Continued goals for this ongoing Outstanding Investigator Grant (OIG) are to develop and use biostatistical, biomathematical and epidemiologic methods aimed at reducing cancer occurrence. The research objectives are twofold: first, to develop new methods for the conduct of epidemiologic studies of cancer etiology in relation to modifiable personal characteristics, and second, to use these methods to collect and analyze data relating such characteristics to site- specific cancer occurrence. Both the statistical and epidemiologic work during the past four years has focussed on cancers of the colorectum, ovary, breast and prostate. The most important research accomplishments have been a study of colorectal cancer in Chinese in the US, Canada and China in relation to diet, physical activity and body size, a collaborative analysis of raw data from 12 US case- control studies of ovarian cancer, and three studies of prostate cancer. This work has been featured in editorials in several scientific journals. Future plans are to address statistical problems and epidemiologic issues that have emerged in the study of cancers of the prostate and ovary. Both the methodological and the epidemiologic effort will focus on improved understanding of the combined effects of hereditary predisposition and modifiable lifestyle characteristics in the etiologies of these cancers.