CARCINOGENESIS MODELING AND RISK ASSESSMENT

描述：（申请人的描述） 近年来，致癌研究已用于解决 的起源、管理和后续行动有关的重大问题 癌 这方面的努力大部分是由于对以下问题的观察所激发的： 发病率和死亡率的人口或观察，在细胞 在哺乳动物系统中。 然而，随着激进的步伐， 癌症生物学正在推进我们对致癌物质的理解， 在这一过程中，需要对这些模型进行评估， 包括现代生物学的信息。 这样做的目的 研讨会将汇集定量和生物科学家， 一个论坛，以促进数学建模的进步， 致癌作用 生物学讲座将集中在当前的理论， 癌症是如何发展和发展的 定量谈判将集中在 癌症建模的最新技术和存在的一些局限性 根据目前的实验结果。 我们会给你足够的机会 两组科学家仔细定义术语， 对概念进行更深入的讨论。

DESCRIPTION: (Applicant's Description) Stochastic modeling in carcinogenesis studies has been used in recent years to address critical issues associated with genesis, management and follow-up of cancer. Much of this effort has been stimulated by observations on morbidity and mortality in populations or observations at t he cellular level in mammalian systems. However, with the radical pace at which cancer biology is advancing our understanding of t he carcinogenic process, these models need to be evaluated for currency and challenged to include information from modern biology. The purpose of this workshop is to bring together quantitative and biological scientists in a forum to stimulate advances in the mathematical modeling of carcinogenesis. Biological talks will focus on the current theories of how cancers develop and process. Quantitative talks will focus on the state-of-the-art in cancer modeling and some of the limitations existing under current experimental findings. Ample opportunity will be given for both groups of scientists to carefully define terms allowing for a more thorough discussion of the concepts.