The impact of early-life adversity on individuals and their descendants

早年逆境对个人及其后代的影响

• 批准号: DP190102975
• 负责人: Prof Rick Richardson
• 金额: $ 26.33万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 2023-04-01
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP190102975
• 关键词: impact; early; life; adversity; individuals

This project aims to determine how early-life stress affects emotional, social, cognitive, and neural processes not only in those directly exposed to such adversity but also in subsequent generations that were only indirectly exposed through their parent's experiences. Past research shows that the adverse effects of early-life stress are pervasive, affecting cognitive, social, and emotional behaviours as well as the body and the brain. The project intends to test the acceleration hypothesis that early-life stress speeds up maturation, especially for behavioural/neural systems involved in fear. Expected outcomes include insights into the mechanisms leading to adult dysfunction. Intended benefits of these insights include the development of effective treatments that can be given early in life.

该项目旨在确定早期生活压力是如何影响情感、社会、认知和神经过程的，不仅是那些直接接触到这种逆境的人，还有那些通过父母的经历间接接触到逆境的后代。过去的研究表明，早期生活压力的负面影响是普遍存在的，影响认知、社会和情感行为，以及身体和大脑。该项目旨在测试早期生活压力加速成熟的假设，特别是涉及恐惧的行为/神经系统。预期的结果包括深入了解导致成人功能障碍的机制。这些见解的预期好处包括开发出可以在生命早期进行的有效治疗方法。