Formation of boundaries in the developing embryo

这个项目旨在解释不同器官之间的界限是如何在发育中的胚胎中建立起来的。该项目旨在确定控制侧板中胚层形成的基因调控网络的组成部分，开发一个可以解释该区域内结构域如何形成的数学模型，并验证斑马鱼体内新的相互作用。该项目的预期结果是揭示我们身体部位的祖细胞是如何在胚胎中被指示放置在正确的时间和正确的位置的。该项目应提供显著的利益，如扩大澳大利亚的知识基础和跨学科科学的研究能力。

This project aims to decipher how the boundaries between the different organs are established in the developing embryo. The project aims to identify the components of the gene regulatory network that controls lateral plate mesoderm formation, develop a mathematical model that can explain how the domains are formed within this region, and validate novel interactions in vivo in zebrafish. The expected outcome of the project is to reveal how the progenitors of our body parts are instructed to be positioned at the right time and at the right place in the embryo. This project should provide significant benefit such as the expansion of Australia's knowledge base and research capability in cross-disciplinary science.