VISUAL HALLUCINATIONS IN ALZHEIMERS DISEASE

阿尔茨海默病的幻视

• 批准号: 2609423
• 负责人: SUZANNE HOLROYD
• 金额: $ 11.88万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2609423
• 关键词: Alzheimer's disease; age difference; agnosia; behavioral /social science research tag; brain disorder chemotherapy; brain imaging /visualization /scanning; cognition; gender difference; hallucinations; hearing disorders; human subject; magnetic resonance imaging; mental health epidemiology; neuroanatomy; occipital lobe /cortex; psychological tests; sensory deprivation; temporal lobe /cortex; vision disorders; vision tests; visual perception

The proposed research focus is psychotic disorders associated with aging. During the award term, a study of visual hallucinations (VH) in Alzheimer's disease (AD) will be conducted, examining correlates to VH including possible neuroanatomic pathology. It is predicted that decreased visual acuity, severity of visual agnosia, history of hearing or visual disorder, female sex, older age, number of medications and temporal and occipital cortical atrophy will associate significantly with VH. This is the first study in my planned program of research to examine psychotic symptoms in AD and other disorders of aging, making linkages of such symptoms to pathophysiology (visual system, brain) where possible.

拟议的研究重点是与衰老相关的精神病。 在奖励期内，对视觉幻觉的研究（VH） 将进行阿尔茨海默氏病（AD），检查与VH相关 包括可能的神经解剖病理学。 可以预测 视力降低，视觉不可思议的严重程度，听力史或 视觉障碍，女性，年龄较大，药物数量和暂时性 枕皮质萎缩将与VH显着相关。 这 是我计划的研究计划中的第一个研究精神病的研究 AD和其他衰老疾病的症状，建立这种联系 可能会在可能的情况下出现病理生理学（视觉系统，大脑）。