OCULOMOTOR RANGE IN HEALTH AND DISEASE

快速转移视线可以通过眼睛的运动来完成， 单独（眼睛扫视）或眼睛和头部的组合运动（眼睛-头部 扫视）。 习惯视力范围（COMR）是指 “中心”眼眶位置，在该位置内，受试者倾向于进行凝视 通过眼睛扫视来改变。先前的研究表明，COMR可能是 大约正负15度，但从未被研究过 系统地COMR很重要，因为：1）其原因 是否存在尚不清楚;它可能反映了大脑能力的局限性 以补偿眼球运动植物，因此绘制COMR将 也映射这些限制; 2）COMR反映了大脑在以下两者之间的选择： 完成给定任务的两种不同方法（即，用一只眼睛- 仅或眼-头扫视）。 这种二元选择过程 电生理技术，但行为研究， COMR是必要的先决条件。 拟议的调查将 确定了眼动仪的测量方法，描述了眼的运动学 在COMR内部和外部进行的移动，确定COMR是否是塑料的， 探讨脑、眶、颈部疾病对COMR的影响。 这些研究还将阐明这些疾病过程对 视觉功能 此外，通过量化眼球运动， 偏心轨道位置，这些研究将建立有效性 以及一些常见的眼动临床测试的局限性。

Rapid shifts of gaze can be accomplished either by movement of the eyes alone (eye saccades) or combined movements of eyes and head (eye-head saccades). The customary oculomotor range (COMR) is that region about "central" orbital position within which a subject tends to make gaze changes by eye saccades. Prior studies suggest that COMR may be approximately plus or minus 15 degrees but it has never been studied systematically. COMR is important because: 1) The reason for its existence is unclear; it may reflect limitations in the brain's ability to compensate for the oculomotor plant, and therefore mapping COMR would also map these limitations; 2) COMR reflects the brain's choice between two different methods of accomplishing a given task (i.e., to use an eye- only or an eye-head saccade). This sort of binary selection process is accessible to electrophysiologic techniques but behavioral studies of COMR are a necessary prerequisite. The proposed investigations would determine methods of measuring COMR, describe the kinematics of eye movements made within and beyond COMR, determine whether COMR is plastic, and examine the effects of diseases of brain, orbit, and neck on COMR. These studies will also clarify the effects of such disease processes on visual function. Furthermore, by quantifying eye movements about eccentric orbital positions, these studies will establish the validity and limitations of some common clinical tests of eye movements.