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OPEN LABEL EXTENDED USE DELAVIRDINE MESYLATE FOR HIV+ PATIENTS

OPEN LABEL EXTENDED USE DELAVIRDINE MESYLATE FOR HIV+ PATIENTS
甲磺酸地拉韦啶开放标签延长用于 HIV 患者
批准号：
6281694
负责人：
PHILIP C JOHNSON
金额：
$1.36万
依托单位：
UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6281694
关键词：
2'3' dideoxycytidine 2'3' dideoxyinosine AIDS therapy HIV infections clinical research combination chemotherapy delavirdine drug screening /evaluation helper T lymphocyte human immunodeficiency virus 1 human subject human therapy evaluation lamivudine polymerase chain reaction stavudine virus RNA zidovudine

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英文摘要
The aim of the protocol is to evaluate the safety and tolerance of long- term triple therapy combination of delavirdine mesylate, AZT, and either ddI or DDC, D4T, or 3TC in HIV positive individuals who were participants in other delavirdine mesylate protocols. The study will also evaluate the efficacy of the triple therapy based on changes in CD4 counts, plasma HIV-1 RNA by PCR, and on time to disease progression or death. Patients will be seen monthly for two years. This study was closed in September, 1997.
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会议论文
COMPARISON OF ANTIRETROVIRAL ACTIVITY OF 3 COMBINATION REGIMENS IN HIV+ PATIENTS
AMBISOME COMPARED WITH AMPHOTERICIN B FOR HISTOPLASMOSIS IN AIDS PTS
COMPARISON OF ANTIRETROVIRAL ACTIVITY OF 3 COMBINATION REGIMENS IN HIV+ PATIENTS
AMBISOME VS AMPHOTERICIN B AND FLUCONAZOLE IN CRYPTOCOCCAL MENINGITIS IN AIDS
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