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AMBISOME COMPARED WITH AMPHOTERICIN B FOR HISTOPLASMOSIS IN AIDS PTS

AMBISOME COMPARED WITH AMPHOTERICIN B FOR HISTOPLASMOSIS IN AIDS PTS
Ambisome 与两性霉素 B 治疗艾滋病患者组织胞浆菌病的比较
批准号：
6121106
负责人：
PHILIP C JOHNSON
金额：
$1.51万
依托单位：
UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6121106
关键词：
AIDS AIDS therapy amphotericin B clinical research combination chemotherapy drug screening /evaluation histoplasmosis human subject human therapy evaluation microorganism disease chemotherapy opportunistic infections

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中文摘要
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英文摘要
The aim of this studyis to compare AmBisome as induction therapy for the treatment of moderate to severe disseminated histoplasmosis in patients with AIDS. Patients will be randomized between treatment with IV AmBisome or amphotericin B for two weeks of induction therapy. Patients will then be treated with itraconazole for 10 additional weeks of consolidation therapy to complete a 12 week treatment course. This is a multicenter study of the Mycoses Study Group. Dr. Johnson is the PI for this nationwide study. The study has reached its total enrollment of 75 and will be analyzed soon.
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