GROWTH HORMONE IN SHORT BOWEL PATIENTS

短肠患者的生长激素

• 批准号: 6281881
• 负责人: Danny O. Jacobs
• 金额: $ 4.73万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6281881
• 关键词: clinical research; clinical trials; diet therapy; gastrointestinal nutrient absorption; human subject; human therapy evaluation; nutrition related tag; parenteral feedings; short bowel syndrome; somatotropin

The purpose of this study is to determine the effect of growth hormone (GH), an investigation drug, on the absorbtion of food ingested. The group of people being studied are those who have lost large segments of intestine and require home parenteral nutrition (TPN). It has been found that administering GH, and changing to a low fat diet containing fiber supplemented with the amino acid glutamine, absorbtion of food and fluid can be improved. Some people have even been removed from TPN.

本研究的目的是确定生长激素的作用 （GH），一种研究药物，对摄入食物的吸收有影响。 这 被研究的人群是那些失去了大部分的 肠道并需要家庭肠外营养（TPN）。 已经找到了 施用 GH，并改为含纤维的低脂饮食 补充氨基酸谷氨酰胺，吸收食物和液体 可以改进。 有些人甚至被从 TPN 中除名。