A new molecular machine required for bacterial development into spores

该项目旨在提供关于细菌如何产生被称为孢子的休眠的、耐压力的细胞，以及细菌如何通过细胞层运输分子来执行生物功能的新知识。在许多细菌病原体中，孢子可以作为新的和反复感染的来源。该项目希望揭示孢子发育所需的一类新的纳米机器的分子细节。产生的新知识可能会扩大分子靶标的武器库，这些分子靶标需要开发干扰孢子形成的策略。这提供了一个平台，工业可以从中吸引投资，探索控制细菌的创新战略。

This project aims to provide new knowledge on how bacteria produce dormant, stress-resistant cells called spores, and how bacteria transport molecules across their cellular layers to execute biological functions. Spores can act as a source of new and recurring infections in many bacterial pathogens. This project expects to reveal molecular details on a new class of nanomachines required for spore development. The new knowledge generated may expand the arsenal of molecular targets required to develop strategies interfering with spore formation. This provides a platform from which industry could attract investment for exploring innovative strategies for controlling bacteria.