SUBGROUPS OF FMS--SYMPTOMS, BELIEFS & TAILORED TREATMENT

纤维肌痛综合征(FMS)是一种普遍存在的慢性肌肉骨骼疼痛 无序。尽管进行了广泛的研究，但病原学和病理生理学 FMS的发病机制尚不清楚，目前尚无治疗方法 被证明是普遍有效的。在这个项目中，我们提出了FMS 是一种复杂的障碍，涉及多种因素，包括身体和 心理社会行为。在我们之前的研究中，我们已经证明 FMS患者在心理社会-行为轴上是不同的 根据它们的不同，可以分为3个不同的亚组 对症状的心理社会适应。在此应用程序中，我们将扩展 我们之前的研究和尝试将治疗与患者相匹配 心理社会--行为特征。具体地说，我们将测试 针对每个心理社会亚群的独特量身定做的治疗效果。 三组FMS患者将接受三种治疗方法中的一种 标准的物理治疗和不同的心理治疗方案 治疗。共有312名FMS患者将接受为期6天的 跨学科治疗课程，包括物理治疗和 心理治疗。所有协议都包括标准化的物理 治疗，但包括认知行为疼痛管理治疗， 人际关系技能培训，或支持性咨询。除了……之外 治疗结果研究，将评估FMS的各种症状 前瞻性地在患者的自然栖息地中更好地了解 FMS症状的协变性。每天重复监测使用 掌上电脑(生态瞬时评估)将允许我们 与回顾报告相比，评估流程评级的价值。 总体而言，这些研究的结果应该确定以下好处 将治疗与受试者的特征相匹配，并增强我们的 认识认知-情感-行为适应的作用 在FMS患者中。

Fibromyalgia syndrome (FMS) is a prevalent, chronic musculoskeletal pain disorder. Despite extensive research the etiology and pathophysiologic mechanisms of FMS are not well understood, and no treatment has been shown to be universally effective. In this project, we propose that FMS is a complex disorder involving multiple factors, both physical and psychosocial-behavioral. In our previous research, we have demonstrated that FMS patients are heterogeneous in the psychosocial-behavioral axis and can be classified into 3 distinct subgroups on a basis of their psychosocial adaptation to symptoms. In this application we will extend our previous research and attempt to match treatments to patients psychosocial-behavioral characteristics. Specifically, we will test the efficacy of uniquely tailored treatment for each psychosocial subgroup. Three groups of FMS patients will be treated with one of the 3 treatment protocols with standard physical therapy and varying psychological treatments. A total of 312 FMS patients will undergo a 6 half-day interdisciplinary treatment sessions consisting of physical therapy and psychological treatments. All protocols include a standardized physical therapy but include either cognitive-behavioral pain management therapy, interpersonal skill training, or supportive counseling. In addition to the treatment outcome study, various symptoms of FMS will be assessed prospectively in the patients natural habitats to better understand covariations of FMS symptoms. The repeated daily monitoring using the palm-top computer (ecological momentary assessment) will permit us to evaluate the value of process ratings compared to retrospective reports. Overall, the results of these studies should establish the benefit of matching treatments to subject characteristics, and enhance our understanding of the roles of cognitive-affective-behavioral adaptation of FMS patients.