权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

INTEGRATION OF ERPS AND FMRI IN STUDIES OF ATTENTION

ERPS 和 FMRI 在注意力研究中的整合

基本信息

批准号：
6165182
负责人：
George R Mangun
金额：
$ 21.82万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
起止时间：
1998-03-20 至 2002-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/6165182
关键词：
attention behavioral /social science research tag clinical research evoked potentials functional magnetic resonance imaging human subject neural information processing neuroanatomy space perception vision visual cortex

项目摘要

DESCRIPTION (Adapted from applicant's abstract): Visual selective attention is a powerful brain mechanism that enables relevant sensory information to be effectively processed, while minimizing interference from irrelevant, distracting events. Despite more than three decades of psychophysical and physiological research, remarkably little is known about the neural mechanisms of this fundamental cognitive process in humans. In particular, precisely how various stages of visual processing are affected by selective spatial attention remains unclear. This proposal will investigate visual selective attention using a combined ERP and fMRI approach that permits both the functional anatomy (fMRI) and time course (ERPs) of attentional processes to be elucidated. The overall goal is to understand the role of selective attention in information processing in the human visual cortex, and to identify the detailed functional architecture of the systems involved. The mechanisms of voluntary spatial attention wi]l be investigated, and the relationship of spatial attention to feature, object and motion processing will be addressed. The proposed experiments have direct theoretical consequences for current physiological models of attentional selection by providing key evidence about both the anatomical locus and time course of attention-related modulations of neural processing in the intact human brain. In addition, because a combined ERP and fMRI approach is to be used, the relationship of electrocortical activity to changes in regional cerebral blood flow (CBF) during information processing will also be studied. Because deficits in attentional processes accompany various psychiatric, neurological and developmental disorders, investigations of the basic properties of human brain attention systems represent important core knowledge in the ongoing struggle to characterize, diagnose and treat such conditions in humans.

描述（改编自申请人摘要）：视觉选择性注意