LOW COST, HIGH QUALITY PREPOLARIZED MRI HEAD SCANNER

描述（改编自申请人摘要）：申请人提出 建立一个超低成本和高品质的原型预极化MRI 用于诊断头部肿瘤的扫描仪。本研究的总体目标是 是开发一种新的和创新的成像方式， 癌症筛查、诊断和图像引导治疗的潜力。 具体目标是设计和建造一个同质的，低场的 电磁铁和低频接收器系统， 显像最终目标是将这些子系统与我们的工作相结合。 预极化MRI系统，并获得正常志愿者的图像 头本研究旨在证明预极化MRI 系统对比度和SNR等同于传统的0.5 T MRI 系统;这种高质量的预极化MRI系统将花费 不到5万美元的资本成本。成功开发和 这项创新技术的整合将需要应用 工程学和科学的几个原则。例如是 均匀电磁体设计方法从电磁学和电磁学两个方面 线性规划。一种低噪声接收机子系统设计 依赖于最佳RF接收器的原理 electronics.脉冲序列设计依赖于MRI的原理 物理学

DESCRIPTION (Adapted from Applicant's Abstract): The applicants proposed to build an ultra-low-cost and high-quality prototype Prepolarized MRI scanner for diagnosing head tumors. The overall goal of this research is to develop a new and innovative imaging modality that shows great potential for cancer screening, diagnosis and image-guided treatment. The specific aims are to design and build both a homogeneous, low-field electromagnet and a lowfrequency receiver system optimized for head imaging. The final aim is to integrate these subsystems with our working Prepolarized MRI system and to obtain an image of a normal volunteers head. This research is intended to demonstrate that Prepolarized MRI system contrast and SNR are equivalent to a conventional 0.5 T MRI system; and that this high-quality Prepolarized MRI system will cost less than $50,000 in capital costs. The successful development and integration of this innovative technology will require the application of several principles of engineering and science. For example, a homogeneous electromagnet design method draws from both electromagnetics and linear programming. A low-noise receiver subsystem design designed by the applicants relies on the principles of optimal RF receiver electronics. Pulse sequence design relies on the principles of MRI physics.