LOW COST, HIGH QUALITY PREPOLARIZED MRI HEAD SCANNER

低成本、高质量预极化 MRI 头部扫描仪

• 批准号: 2729448
• 负责人: ALBERT MACOVSKI
• 金额: $ 15.24万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-05-01 至 2001-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2729448
• 关键词: bioimaging /biomedical imaging; biomedical equipment development; clinical biomedical equipment; head /neck neoplasm; magnetic resonance imaging; neoplasm /cancer diagnosis

DESCRIPTION (Adapted from Applicant's Abstract): The applicants proposed to build an ultra-low-cost and high-quality prototype Prepolarized MRI scanner for diagnosing head tumors. The overall goal of this research is to develop a new and innovative imaging modality that shows great potential for cancer screening, diagnosis and image-guided treatment. The specific aims are to design and build both a homogeneous, low-field electromagnet and a lowfrequency receiver system optimized for head imaging. The final aim is to integrate these subsystems with our working Prepolarized MRI system and to obtain an image of a normal volunteers head. This research is intended to demonstrate that Prepolarized MRI system contrast and SNR are equivalent to a conventional 0.5 T MRI system; and that this high-quality Prepolarized MRI system will cost less than $50,000 in capital costs. The successful development and integration of this innovative technology will require the application of several principles of engineering and science. For example, a homogeneous electromagnet design method draws from both electromagnetics and linear programming. A low-noise receiver subsystem design designed by the applicants relies on the principles of optimal RF receiver electronics. Pulse sequence design relies on the principles of MRI physics.

简介(改编自申请人摘要)：建议的申请人 构建超低成本、高质量的预极化磁共振成像原型 用于诊断头部肿瘤的扫描仪。这项研究的总体目标 是开发一种新的、创新的成像模式，显示出 在癌症筛查、诊断和图像引导治疗方面的潜力。 具体目标是设计和建造一个均匀的低场 电磁铁和针对磁头优化的低频接收系统 成像。最终目标是将这些子系统与我们的工作集成在一起 预极化磁共振成像系统和获得正常志愿者的图像 头。这项研究旨在证明预极化核磁共振 系统对比度和信噪比相当于常规的0.5T磁共振成像 这种高质量的预极化核磁共振成像系统将花费 资本成本不到5万美元。成功的开发和 这项创新技术的集成将需要应用 工程和科学的几个原理。例如，一个 一种借鉴两种电磁学的均匀电磁铁设计方法 和线性规划。一种低噪声接收子系统的设计 申请人所依赖的原则是最佳的射频接收器 电子产品。脉冲序列设计依赖于磁共振成像原理 物理学。