LOW COST, HIGH QUALITY PREPOLARIZED MRI HEAD SCANNER

低成本、高质量预极化 MRI 头部扫描仪

• 批准号: 6173719
• 负责人: ALBERT MACOVSKI
• 金额: $ 15.32万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-05-01 至 2002-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6173719
• 关键词: bioimaging /biomedical imaging; biomedical equipment development; clinical biomedical equipment; head /neck neoplasm; magnetic resonance imaging; neoplasm /cancer diagnosis

DESCRIPTION (Adapted from Applicant's Abstract): The applicants proposed to build an ultra-low-cost and high-quality prototype Prepolarized MRI scanner for diagnosing head tumors. The overall goal of this research is to develop a new and innovative imaging modality that shows great potential for cancer screening, diagnosis and image-guided treatment. The specific aims are to design and build both a homogeneous, low-field electromagnet and a lowfrequency receiver system optimized for head imaging. The final aim is to integrate these subsystems with our working Prepolarized MRI system and to obtain an image of a normal volunteers head. This research is intended to demonstrate that Prepolarized MRI system contrast and SNR are equivalent to a conventional 0.5 T MRI system; and that this high-quality Prepolarized MRI system will cost less than $50,000 in capital costs. The successful development and integration of this innovative technology will require the application of several principles of engineering and science. For example, a homogeneous electromagnet design method draws from both electromagnetics and linear programming. A low-noise receiver subsystem design designed by the applicants relies on the principles of optimal RF receiver electronics. Pulse sequence design relies on the principles of MRI physics.

描述（根据申请人的摘要改编）：申请人提议 建立超低成本和高质量的原型预校准MRI 用于诊断头部肿瘤的扫描仪。这项研究的总体目标 是开发一种新的创新成像方式，显示出很棒的 癌症筛查，诊断和图像引导治疗的潜力。 具体的目的是设计和建造同质的低场 电磁体和针对头部优化的低频接收器系统 成像。最终目的是将这些子系统与我们的工作 预算力的MRI系统并获得正常志愿者的图像 头。这项研究旨在证明propallarized MRI 系统对比和SNR等于常规0.5 T MRI 系统;而且这种高质量的预校准MRI系统将花费 不到$ 50,000的资本成本。成功的发展和 这种创新技术的集成将需要应用 工程和科学原则。例如， 均匀的电磁设计方法均从两种电磁学中绘制 和线性编程。设计的低噪声接收器子系统设计 申请人依赖于最佳RF接收器的原理 电子产品。脉冲序列设计取决于MRI的原理 物理。