7TH CONFERENCE: DRUG ABUSE, IMMUNOMODULATION & AIDS

描述：申请者摘要 药物滥用、免疫调节和艾滋病问题系列会议第七次会议将举行 将于1999年10月7日至9日(星期四至星期六)在美国国立卫生研究院校园举行 马苏尔礼堂(10号楼)。会议的题目是《神经免疫》 《相互作用与疾病》对神经免疫轴作用的认识 在调节感染和疾病过程中。这次会议将跨越 从基础研究到配体及其受体的广泛领域 通过这些变化来调节免疫和神经功能 对疾病的进展和感染性病原体的表达有影响 这些过程可能会产生临床表现。在这些领域中，有两个 重点将是最重要的--药物成瘾对这些相互作用的影响 由此产生的对表现形式的更改或缺失，以及 艾滋病毒向艾滋病的进展。出席会议的演讲者将展示他们最 从试管到动物的各种模型的最新数据 模型与人类临床相关。演讲将回答一些问题。 病毒在外周免疫系统中的复制和突变，转移 病毒对神经系统的作用及其在那里的表达和作用 各种因素在加速或延缓感染过程中发挥作用。这个 将仔细讨论滥用毒品的作用，以确定它是否 对进步具有重要意义。演讲方式将包括座谈会 课程将提供对个别主题的概述，课程包括 来自调查员实验室的最新数据，海报演示和 在每一次会议结束时的讨论小组。参与者将 包括临床医生和科学家以及一群年轻的科学家，他们 参与活动将由会议颁发的青年调查员奖提供便利 格兰特。一如既往，会议成果将及时公布 作为一本全会出版的书籍或《中国日报》的独立卷 神经免疫学。

DESCRIPTION: Applicant's Abstract The 7th Conference in the series on Drug Abuse, Immunomodulation and AIDS will take place on October 7-9, 1999 (Thursday-Saturday) on the NIH campus in the Masur Auditorium (Building 10). The conference title will be "Neuroimmune Interactions and Disease" in recognition of the role the neuroimmune axis plays in modulating infection and the disease process. The conference will span the broad area from basic research into the ligands and their receptors which modulate immune and neuronal function, through the effect that these changes have on disease progression and expression of the infectious agent, to the clinical manifestations these processes might engender. Within these areas, two foci will be paramount-the effects of drug addiction on these interactions and the resultant alterations, or lack thereof, on the manifestation and progression of HIV to AIDS. Speakers at the meeting will present their most recent data on a variety of models from the test tube in vitro through animal models to human clinical correlates. The presentations will address questions of viral replication and mutation in the peripheral immune system, of transfer of the virus to the neuronal system and its expression there and of the role various factors play in accelerating or retarding the infectious process. The role of drugs of abuse will be carefully discussed to determine whether it is significant to the progression. The mode of presentation will include symposium lectures which will provide overviews of individual topics, lectures featuring recent data from the investigator's laboratory, poster presentations and discussion groups at the end of each of the sessions. The participants will include clinicians and bench scientists plus a group of young scientists whose participation will be facilitated by Young Investigator Awards from the meeting grant. As in the past, the results of the meeting will be published in a timely manner either as a Plenum Press book or an independent volume of the Journal of Neuroimmunology.