CORE--LABORATORY CORE

核心--实验室核心

• 批准号: 3839487
• 负责人: CHRISTOPHER A SQUIER
• 金额: --
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3839487
• 关键词: biomedical facility; clinical trials; dental research; dentistry education; disease /disorder proneness /risk; human subject

The role of the Laboratory Core will be to provide the facilities and expertise to most efficiently assist investigators in basic and laboratory studies related to clinical problems. This will be achieved by offering a Core of four laboratories each with an experienced basic scientist as a Coordinator. In addition, the Collegiate Core Research Services will provide routine support with standard laboratory procedures and the University Centralized Research Facilities will offer sophisticated equipment and state-of-the-art methodology. The Core will be directed by Dr. C. Squier, Assistant Dean for Research and Director of the Dows Institute at the College of Dentistry. The Laboratory Coordinators will meet regularly with the Director and investigators to advise on the conduct and progress of studies. This concept will provide flexible laboratory support with the methodology most appropriate to the type of clinical research being undertaken. Training will be offered to investigators by provision of both formal courses and by individual mentoring. The research to be supported will include Center Pilot Projects as well as extensions of existing independently funded projects into areas relevant to the aims of the NIDR Research and Action Program. In the first two years, this will represent 3 pilot projects together utilizing each of the core laboratories, and the joint use facilities, and extensions of independently funded projects utilizing three of the core laboratories. Together this clinical research will provide a significant contribution to improving the oral health of older patients and individuals at high risk.

实验室核心的作用是提供设施和 最有效地协助基础和实验室研究人员的专业知识 与临床问题相关的研究。 这将通过提供一个来实现 四个实验室的核心，每个实验室都有一位经验丰富的基础科学家作为 协调员。 此外，大学核心研究服务将 通过标准实验室程序和 大学集中研究设施将提供先进的 设备和最先进的方法。 核心将由 C. Squier 博士，研究助理院长兼陶氏化学研究所所长 牙科学院研究所。 实验室协调员将 定期与主任和调查员会面，就行为提出建议 以及学业进展。 这一概念将提供灵活的实验室 使用最适合临床类型的方法提供支持 正在进行研究。 将为调查人员提供培训 提供正式课程和个人辅导。 受支持的研究将包括中心试点项目以及 将现有独立资助的项目扩展到相关领域 NIDR 研究和行动计划的目标。 在最初的两年里， 这将代表 3 个试点项目，共同利用每个核心 实验室、联合使用设施以及独立的扩建 资助利用三个核心实验室的项目。 一起这个 临床研究将为改善疾病做出重大贡献 老年患者和高危人群的口腔健康。