CORE--LABORATORY CORE

核心--实验室核心

• 批准号: 3775950
• 负责人: CHRISTOPHER A SQUIER
• 金额: --
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3775950
• 关键词: biomedical facility; clinical trials; dental research; dentistry education; disease /disorder proneness /risk; human subject

The role of the Laboratory Core will be to provide the facilities and expertise to most efficiently assist investigators in basic and laboratory studies related to clinical problems. This will be achieved by offering a Core of four laboratories each with an experienced basic scientist as a Coordinator. In addition, the Collegiate Core Research Services will provide routine support with standard laboratory procedures and the University Centralized Research Facilities will offer sophisticated equipment and state-of-the-art methodology. The Core will be directed by Dr. C. Squier, Assistant Dean for Research and Director of the Dows Institute at the College of Dentistry. The Laboratory Coordinators will meet regularly with the Director and investigators to advise on the conduct and progress of studies. This concept will provide flexible laboratory support with the methodology most appropriate to the type of clinical research being undertaken. Training will be offered to investigators by provision of both formal courses and by individual mentoring. The research to be supported will include Center Pilot Projects as well as extensions of existing independently funded projects into areas relevant to the aims of the NIDR Research and Action Program. In the first two years, this will represent 3 pilot projects together utilizing each of the core laboratories, and the joint use facilities, and extensions of independently funded projects utilizing three of the core laboratories. Together this clinical research will provide a significant contribution to improving the oral health of older patients and individuals at high risk.

实验室核心的作用是提供设施， 专业知识，以最有效地协助研究人员在基础和实验室 与临床问题相关的研究。 这将通过提供一个 四个实验室的核心，每个实验室都有一位经验丰富的基础科学家作为 协调员很 此外，学院核心研究服务将 提供标准实验室程序的常规支持， 大学集中研究设施将提供先进的 设备和最先进的方法 核心将由 博士C.斯奎尔，研究助理院长兼道斯主任 在牙科学院的研究所。 实验室协调员将 定期与主任和调查人员会面，就行为提供意见 和研究进展。 这一概念将提供灵活的实验室 支持最适合临床类型的方法 正在进行的研究。 将通过以下方式向研究者提供培训： 提供正式课程和个别辅导。 支持的研究将包括中心试点项目以及 将现有的独立供资项目扩展到与下列方面有关的领域： NIDR研究和行动计划的目标。 在头两年， 这将代表3个试点项目， 实验室，和共同使用的设施，并独立扩展 利用三个核心实验室资助的项目。 一起这么 临床研究将为改善 老年患者和高危人群的口腔健康。