权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Cell specific expression of genes in C4 photosynthesis

C4光合作用基因的细胞特异性表达

基本信息

批准号：
BB/I002243/1
负责人：
Julian Hibberd
金额：
$ 43.03万
依托单位：
University of Cambridge
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2011
资助国家：
英国
起止时间：
2011 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=BB%2FI002243%2F1
关键词：
Cell specific expression genes C4

项目摘要

By 2050, due to population growth we will need at least 50% more food than today. However, increases in the maximum yield of crops such as rice have plateaued. There are few biological precedents that show that yields can be increased by this order of magnitude, but C4 photosynthesis is one of them. It has therefore been proposed that placing characteristics of C4 photosynthesis into crops that currently use the less efficient C3 pathway should be attempted. Before this is feasible, we need a better basic understanding of how the C4 pathway operates. We have recently identified a region that is shared by multiple genes, and that generates BS specificity in leaves of the C4 plant C. gynandra. This is the first example of cell specificity in C4 leaves being generated by information within coding regions. In addition, this region is already present in orthologous genes from C3 species, and so shows that genes can be directly recruited into cell specific expression in C4 leaves without any change in sequence. We aim to define the nucleotides present in this region that generate BS specificity, to determine the extent to which other genes in the C4 cycle are regulated by elements within their coding regions, and also to define the extent to which genes from C3 species already possess elements that generate M or BS specificity in C4 leaves.

到2050年，由于人口增长，我们将需要比现在多50%的食物。然而，水稻等作物最高产量的增长已经停滞。很少有生物学先例表明产量可以增加这个数量级，但C4光合作用是其中之一。因此，有人提出，应尝试将C4光合作用的特性引入目前使用效率较低的C3途径的作物中。在这可行之前，我们需要更好地了解C4途径的运作方式。我们最近已经确定了一个区域，这是由多个基因共享，并产生BS特异性的C4植物C。gynandra。这是C4叶中细胞特异性由编码区内的信息产生的第一个例子。此外，该区域已经存在于来自C3物种的直向同源基因中，因此表明基因可以直接募集到C4叶中的细胞特异性表达中而没有任何序列变化。我们的目标是确定该区域中存在的产生BS特异性的核苷酸，以确定C4循环中的其他基因在多大程度上受其编码区内的元件的调节，并且还确定来自C3物种的基因在多大程度上已经具有在C4叶中产生M或BS特异性的元件。

项目成果

期刊论文数量（10）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

A high throughput gas exchange screen for determining rates of photorespiration or regulation of C4 activity.

DOI：
10.1093/jxb/eru238
发表时间：
2014-07
期刊：
Journal of experimental botany
影响因子：
6.9
作者：
Bellasio C;Burgess SJ;Griffiths H;Hibberd JM
通讯作者：
Hibberd JM

Ancestral light and chloroplast regulation form the foundations for C4 gene expression.

祖先的光和叶绿体调节构成了 C4 基因表达的基础。

DOI：
10.17863/cam.5952
发表时间：
2016
期刊：
影响因子：
0
作者：
Burgess S
通讯作者：
Burgess S

Arabidopsis uses two gluconeogenic gateways for organic acids to fuel seedling establishment.

DOI：
10.1038/ncomms7659
发表时间：
2015-04-10
期刊：
NATURE COMMUNICATIONS
影响因子：
16.6
作者：
Eastmond, Peter J.;Astley, Holly M.;Parsley, Kate;Aubry, Sylvain;Williams, Ben P.;Menard, Guillaume N.;Craddock, Christian P.;Nunes-Nesi, Adriano;Fernie, Alisdair R.;Hibberd, Julian M.
通讯作者：
Hibberd, Julian M.

Ancestral light and chloroplast regulation form the foundations for C4 gene expression