Triticeae Genomics for Sustainable Agriculture

小麦科基因组学促进可持续农业

• 批准号: BB/J003913/1
• 负责人: Andrew Phillips
• 金额: $ 4.69万
• 依托单位: Rothamsted Research
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2012
• 资助国家: 英国
• 起止时间: 2012 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FJ003913%2F1
• 关键词: Triticeae; Genomics; Sustainable; Agriculture

Securing food supply on a global scale requires solutions to a complex set of unprecedented problems, including rising demand due to major population increases and social mobility, global climate change, rising energy costs and land, water and nutrient limitations. Finding and implementing these solutions is a top priority for governments and scientists worldwide, and has been articulated as a key BBSRC strategic objective. Opportunities for plant science to contribute to global food security include increasing the yield and quality of crops, combatting diseases, enabling maximal crop productivity in sub-optimal growth conditions, and increasing maximal yield potential. Utilising non- food components of food crops, such as cell wall material and waste products of food production to produce energy and industrial feedstocks, has a major role in reaching sustainability and maximising overall yield of renewable resources from limited land and soils. Grass crops are essential for human existence by directly or indirectly serving as the primary source of human nutrition. Wheat, rice and coarse grains such as maize are the most important crops for human food production, therefore increasing grain production sustainably is a critically important strategic and scientific objective. Wheat is the main arable crop in the UK, planted on 60% of arable land, with an annual farm gate value of ~£2.5b and a processed product value of approximately £150bn. Yield increases in wheat are slowing compared to past gains achieved primarily through improved agronomy and also in relation to other grain crops, notably maize. Genetic and transgenic improvement of wheat is therefore a very high priority in the UK and world- wide, and large international programmes for wheat genetic improvement are underway. A high quality genomics sequence provides a complete, accurate and durable record of genes, predicted proteins and other genomic elements that today are a fundamental foundation for nearly all areas of biological research. This proposal describes a UK component of an international coordinated wheat genome sequencing project that will make decisive and innovative contributions to sequencing the wheat genome and supporting crop improvement through genomics.

确保全球范围的粮食供应需要解决一系列前所未有的复杂问题，包括人口大幅增加和社会流动性导致的需求增加、全球气候变化、能源成本上升以及土地、水和营养有限。寻找和实施这些解决方案是世界各国政府和科学家的首要任务，也是BBSRC的关键战略目标。植物科学为全球粮食安全做出贡献的机会包括提高作物的产量和质量，防治疾病，在次优生长条件下实现最大作物生产力，以及提高最大产量潜力。利用粮食作物的非粮食成分，如细胞壁材料和粮食生产的废物来生产能源和工业原料，在实现可持续性和从有限的土地和土壤中最大限度地提高可再生资源的总产量方面发挥着重要作用。禾本科作物直接或间接地作为人类营养的主要来源，对人类的生存至关重要。小麦、水稻和玉米等粗粮是人类最重要的粮食生产作物，因此可持续地增加粮食产量是一个至关重要的战略和科学目标。小麦是英国主要的可耕地作物，种植在60%的耕地上，每年的农场价值约为25亿英镑，加工产品价值约为1500亿英镑。与过去主要通过改进农艺取得的收益相比，小麦的产量增长正在放缓，与其他粮食作物，特别是玉米相比，小麦的产量增长也在放缓。因此，小麦的遗传和转基因改良在英国和世界范围内都是非常优先的，并且正在进行小麦遗传改良的大型国际计划。高质量的基因组学序列提供了基因、预测蛋白质和其他基因组元素的完整、准确和持久的记录，这些基因组元素是当今几乎所有生物研究领域的基础。该提案描述了国际协调小麦基因组测序项目的英国组成部分，该项目将为小麦基因组测序和通过基因组学支持作物改良做出决定性和创新性贡献。

项目成果

Genome sequence of the progenitor of the wheat D genome Aegilops tauschii.

• DOI: 10.1038/nature24486
• 发表时间: 2017-11-23
• 期刊: Nature
• 影响因子: 64.8
• 作者: Luo MC;Gu YQ;Puiu D;Wang H;Twardziok SO;Deal KR;Huo N;Zhu T;Wang L;Wang Y;McGuire PE;Liu S;Long H;Ramasamy RK;Rodriguez JC;Van SL;Yuan L;Wang Z;Xia Z;Xiao L;Anderson OD;Ouyang S;Liang Y;Zimin AV;Pertea G;Qi P;Bennetzen JL;Dai X;Dawson MW;Müller HG;Kugler K;Rivarola-Duarte L;Spannagl M;Mayer KFX;Lu FH;Bevan MW;Leroy P;Li P;You FM;Sun Q;Liu Z;Lyons E;Wicker T;Salzberg SL;Devos KM;Dvořák J
• 通讯作者: Dvořák J

An improved assembly and annotation of the allohexaploid wheat genome identifies complete families of agronomic genes and provides genomic evidence for chromosomal translocations.

• DOI: 10.1101/gr.217117.116
• 发表时间: 2017-05
• 期刊: Genome research
• 影响因子: 7
• 作者: Clavijo BJ;Venturini L;Schudoma C;Accinelli GG;Kaithakottil G;Wright J;Borrill P;Kettleborough G;Heavens D;Chapman H;Lipscombe J;Barker T;Lu FH;McKenzie N;Raats D;Ramirez-Gonzalez RH;Coince A;Peel N;Percival-Alwyn L;Duncan O;Trösch J;Yu G;Bolser DM;Namaati G;Kerhornou A;Spannagl M;Gundlach H;Haberer G;Davey RP;Fosker C;Palma FD;Phillips AL;Millar AH;Kersey PJ;Uauy C;Krasileva KV;Swarbreck D;Bevan MW;Clark MD
• 通讯作者: Clark MD

mlo-based powdery mildew resistance in hexaploid bread wheat generated by a non-transgenic TILLING approach.

• DOI: 10.1111/pbi.12631
• 发表时间: 2017-03
• 期刊: Plant biotechnology journal
• 影响因子: 13.8
• 作者: Acevedo-Garcia J;Spencer D;Thieron H;Reinstädler A;Hammond-Kosack K;Phillips AL;Panstruga R
• 通讯作者: Panstruga R

Loss of TaIRX9b gene function in wheat decreases chain length and amount of arabinoxylan in grain but increases cross-linking.

小麦中TAIRX9B基因功能的丧失会降低晶粒中的链长和阿拉伯素的量，但会增加交联。

• DOI: 10.1111/pbi.13393
• 发表时间: 2020-11
• 期刊: Plant biotechnology journal
• 影响因子: 13.8
• 作者: Pellny TK;Patil A;Wood AJ;Freeman J;Halsey K;Plummer A;Kosik O;Temple H;Collins JD;Dupree P;Berry S;Shewry PR;Lovegrove A;Phillips AL;Mitchell RAC
• 通讯作者: Mitchell RAC

Mutation Scanning in Wheat by Exon Capture and Next-Generation Sequencing.

• DOI: 10.1371/journal.pone.0137549
• 发表时间: 2015
• 期刊: PloS one
• 影响因子: 3.7
• 作者: King R;Bird N;Ramirez-Gonzalez R;Coghill JA;Patil A;Hassani-Pak K;Uauy C;Phillips AL
• 通讯作者: Phillips AL