STATIC FORCE AND STABILITY ANALYSIS OF HUMAN ELBOW

人体肘部静力及稳定性分析

• 批准号: 3155400
• 负责人: KAI-NAN AN
• 金额: $ 15.74万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 1979
• 资助国家: 美国
• 起止时间: 1979-12-01 至 1992-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3155400
• 关键词: arthroplasty; articular cartilage; biomechanics; clinical biomedical equipment; computer simulation; elbow; electromyography; joint ligament; joint prosthesis; mechanical stress; muscle stress; rehabilitation; skeletal stress

The long-term goal of this study is to address the problems of elbow joint dysfunction and reconstructive surgery. Biomechanically, it is important to characterize 1) the mechanical environment and requirements imposed on the elbow joint in daily and recreational activities, and 2) the pathologic motion loss, weakness, and instability, thereby defining the functional impairment to be corrected or addressed by reconstructive surgery. A detailed analysis of the reconstructed elbow joint under these mechanical environments will allow definition of the objective benefits of the surgery and provide a basis for selecting a given procedure. The specific aims of this study are: (1) to analyze the muscle and joint forces across the elbow joint resulting from selected activities of daily living and (2) to compare the constraint and stability of five types of prostheses for elbow joint replacement. To achieve these two specific goals, both the analytic and experimental methods developed in past years will be used. The kinematics and external load application on the segments distal to the elbow joint will be collected for 10 selected activities by combined use of the electromagnetic tracking system, electrogoniometers, and load cells. The intersegmental forces and moments about the elbow joint due to inertial effects as well as external loading will be calculated using the three-dimensional DYNAMIC model developed. Finally, the specific muscle and joint resultant forces and moments will be calculated using the MUSCLE model. This study will be accomplished by using 40 normal subjects, 20 of each sex ranging in age from 50-60 years. Joint constraint and stability performance will be used to compare the five selected designs of prostheses for elbow joint reconstruction and replacement, each of which is currently available and represents a unique design feature and concept. Experimentally, the joint stability or laxity in cadaveric specimens with prosthetic replacements will be quantitated by using the joint kinematic analysis. Movement of the elbow joint will be achieved with simulated muscle loading as well as additional valgus-varus stress. Changes in the pattern and magnitude of the axes of rotation will be used to assess the joint constraint. In addition, the mechanical advantage of each muscle around the replaced joint will be calculated based on the tendon excursion and joint rotation. Sensitivity analysis will also be performed to analyze the effects of surgical placement of these prostheses and soft tissue reconstruction.

本研究的长期目标是解决以下问题： 肘关节功能障碍和重建手术。 从生物力学上讲，重要的是表征1）机械 日常生活中对手肘关节的环境和要求 和娱乐活动，以及2）病理性运动丧失， 虚弱和不稳定，从而定义了功能 通过重建手术纠正或解决损伤。 本文详细分析了在这些条件下重建肘关节的情况， 机械环境将允许定义目标 手术的好处，并为选择给定的 procedure. 本研究的具体目的是：（1）分析 手肘关节上的肌肉和关节力， 选择的日常生活活动和（2）比较 五种肘关节假体的约束和稳定性 关节置换 为了实现这两个具体目标， 过去几年开发的分析和实验方法将 采用 远端节段的运动学和外载荷作用 将为10项选定的活动收集手肘关节的损伤情况， 结合使用电磁跟踪系统， 电测角器和测压元件。 节间力和 由于惯性效应引起手肘关节力矩以及 外部载荷将使用三维 动态模型开发。 最后，特定的肌肉和关节 将使用肌肉计算合力和力矩 模型 这项研究将通过使用40个正常的 受试者，男女各20名，年龄范围为50-60岁。 关节约束和稳定性能将用于比较 五种肘关节假体设计 重建和更换，每一个都是目前 它代表了独特的设计特征和概念。 在实验上，关节的稳定性或松弛度在尸体 将使用以下方法对带有假体置换的标本进行定量： 关节运动学分析。 手肘关节的运动将是 通过模拟肌肉负荷以及额外的 外翻-内翻应力 全球化模式和规模的变化 旋转轴将用于评估关节约束。 在 此外，每个肌肉周围的机械优势 将根据肌腱偏移计算置换关节， 关节旋转 还将进行敏感性分析， 分析这些假体的手术放置效果， 软组织重建