Integrating systems biology and transgenic technologies to unlock the secrets of Sertoli cell development and function

整合系统生物学和转基因技术来解开支持细胞发育和功能的秘密

• 批准号: BB/J016209/1
• 负责人: Peter O'Shaughnessy
• 金额: $ 32.94万
• 依托单位: University of Glasgow
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2012
• 资助国家: 英国
• 起止时间: 2012 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FJ016209%2F1
• 关键词: Integrating; systems; biology; transgenic; technologies

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前，所有资助研究的摘要都不能在GTR中找到。这通常是因为在提交提案时并不需要摘要，但可能是因为它包含了个人详细信息等敏感信息。

项目成果

Testicular Cell Selective Ablation Using Diphtheria Toxin Receptor Transgenic Mice.

使用白喉毒素受体转基因小鼠进行睾丸细胞选择性消融。

• DOI: 10.1007/978-1-4939-7698-0_15
• 发表时间: 2018
• 期刊: Methods in molecular biology (Clifton, N.J.)
• 作者: Rebourcet D

Cell-specific ablation in the testis: what have we learned?

• DOI: 10.1111/andr.12107
• 发表时间: 2015-11
• 期刊: Andrology
• 影响因子: 4.5
• 作者: Smith LB;O'Shaughnessy PJ;Rebourcet D
• 通讯作者: Rebourcet D

Additional file 1: of Identification of Sertoli cell-specific transcripts in the mouse testis and the role of FSH and androgen in the control of Sertoli cell activity

附加文件1：小鼠睾丸中支持细胞特异性转录物的鉴定以及FSH和雄激素在控制支持细胞活性中的作用

• DOI: 10.6084/m9.figshare.5708995
• 发表时间: 2017
• 作者: U. Soffientini

Modelling the Structure and Dynamics of Biological Pathways.

生物途径的结构和动力学建模。

• DOI: 10.1371/journal.pbio.1002530
• 发表时间: 2016-08
• 期刊: PLoS biology
• 影响因子: 9.8
• 作者: O'Hara L;Livigni A;Theo T;Boyer B;Angus T;Wright D;Chen SH;Raza S;Barnett MW;Digard P;Smith LB;Freeman TC
• 通讯作者: Freeman TC

Sertoli Cells Modulate Testicular Vascular Network Development, Structure, and Function to Influence Circulating Testosterone Concentrations in Adult Male Mice.

• DOI: 10.1210/en.2016-1156
• 发表时间: 2016-06
• 期刊: Endocrinology
• 影响因子: 4.8
• 作者: Rebourcet D;Wu J;Cruickshanks L;Smith SE;Milne L;Fernando A;Wallace RJ;Gray CD;Hadoke PW;Mitchell RT;O'Shaughnessy PJ;Smith LB
• 通讯作者: Smith LB