Integrating cAMP- and nitric oxide- signalling in Mycobacterium tuberculosis: novel regulatory networks that challenge established paradigms

在结核分枝杆菌中整合 cAMP 和一氧化氮信号传导：挑战既定范例的新型调控网络

• 批准号: BB/K000330/1
• 负责人: Galina Mukamolova
• 金额: $ 40.25万
• 依托单位: University of Leicester
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2013
• 资助国家: 英国
• 起止时间: 2013 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FK000330%2F1
• 关键词: Integrating; cAMP; nitric; oxide; signalling

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

Efficient Protein Digestion at Elevated Temperature in the Presence of Sodium Dodecyl Sulfate and Calcium Ions for Membrane Proteomics.

在十二烷基硫酸钠和钙离子存在下，在高温下高效消化蛋白质，用于膜蛋白质组学。

• DOI: 10.1021/acs.analchem.9b00484
• 发表时间: 2019
• 期刊: Analytical chemistry
• 影响因子: 7.4
• 作者: Loraine J

A Persistent Tuberculosis Outbreak in the UK Is Characterized by Hydrophobic fadB4-Deficient Mycobacterium tuberculosis That Replicates Rapidly in Macrophages.

• DOI: 10.1128/mbio.02656-22
• 发表时间: 2022-12-20
• 期刊: mBio
• 影响因子: 6.4
• 作者: Farzand R;Haigh RD;Monk P;Haldar P;Patel H;Pareek M;Verma R;Barer MR;Woltmann G;Ahyow L;Jagatia H;Decker J;Mukamolova GV;Cooper AM;Garton NJ;O'Hare HM
• 通讯作者: O'Hare HM

Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the global transcriptional regulator Lsr2

蛋白激酶 B 通过全局转录调节因子 Lsr2 的磷酸化来控制结核分枝杆菌的生长

• DOI: 10.1101/571406
• 发表时间: 2019
• 作者: Alqaseer K

Difference in persistent tuberculosis bacteria between in vitro and sputum from patients: implications for translational predictions.

• DOI: 10.1038/s41598-020-72472-y
• 发表时间: 2020-09-23
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Faraj A;Clewe O;Svensson RJ;Mukamolova GV;Barer MR;Simonsson USH
• 通讯作者: Simonsson USH

Development of an In Vitro Assay for Detection of Drug-Induced Resuscitation-Promoting-Factor-Dependent Mycobacteria.

• DOI: 10.1128/aac.00518-16
• 发表时间: 2016-10
• 期刊: Antimicrobial agents and chemotherapy
• 影响因子: 4.9
• 作者: Loraine J;Pu F;Turapov O;Mukamolova GV
• 通讯作者: Mukamolova GV