Advanced iron-specific spectroscopies for the study of iron-sulfur cluster transcriptional regulators

用于研究铁硫簇转录调节因子的先进铁特异性光谱

• 批准号: BB/K02115X/1
• 负责人: Nicolas Le Brun
• 金额: $ 4.73万
• 依托单位: University of East Anglia
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2013
• 资助国家: 英国
• 起止时间: 2013 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FK02115X%2F1
• 关键词: Advanced; iron; specific; spectroscopies; study

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前，所有资助研究的摘要都不能在GTR中找到。这通常是因为在提交提案时并不需要摘要，但可能是因为它包含了个人详细信息等敏感信息。

项目成果

Nitrosylation of Nitric-Oxide-Sensing Regulatory Proteins Containing [4Fe-4S] Clusters Gives Rise to Multiple Iron-Nitrosyl Complexes

含有 [4Fe-4S] 簇的一氧化氮感应调节蛋白的亚硝基化产生多个铁-亚硝酰基复合物

• DOI: 10.1002/ange.201607033
• 发表时间: 2016
• 期刊: Angewandte Chemie
• 作者: Serrano P

NsrR from Streptomyces coelicolor is a nitric oxide-sensing [4Fe-4S] cluster protein with a specialized regulatory function.

• DOI: 10.1074/jbc.m115.643072
• 发表时间: 2015-05-15
• 期刊: The Journal of biological chemistry
• 作者: Crack JC;Munnoch J;Dodd EL;Knowles F;Al Bassam MM;Kamali S;Holland AA;Cramer SP;Hamilton CJ;Johnson MK;Thomson AJ;Hutchings MI;Le Brun NE
• 通讯作者: Le Brun NE

Nitrosylation of Nitric-Oxide-Sensing Regulatory Proteins Containing [4Fe-4S] Clusters Gives Rise to Multiple Iron-Nitrosyl Complexes.

• DOI: 10.1002/anie.201607033
• 发表时间: 2016-11-14
• 期刊: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
• 影响因子: 16.6
• 作者: Serrano, Pauline N.;Wang, Hongxin;Crack, Jason C.;Prior, Christopher;Hutchings, Matthew I.;Thomson, Andrew J.;Kamali, Saeed;Yoda, Yoshitaka;Zhao, Jiyong;Hu, Michael Y.;Alp, Ercan E.;Oganesyan, Vasily S.;Le Brun, Nick E.;Cramer, Stephen P.
• 通讯作者: Cramer, Stephen P.