The structure and function of SGTA, a key regulator of protein quality control

蛋白质质量控​​制关键调节因子SGTA的结构和功能

• 批准号: BB/L006952/1
• 负责人: Rivka Isaacson
• 金额: $ 42.5万
• 依托单位: King's College London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2014
• 资助国家: 英国
• 起止时间: 2014 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FL006952%2F1
• 关键词: structure; function; SGTA; key; regulator

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

Structural and functional insights into the E3 ligase, RNF126.

• DOI: 10.1038/srep26433
• 发表时间: 2016-05-19
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Krysztofinska EM;Martínez-Lumbreras S;Thapaliya A;Evans NJ;High S;Isaacson RL
• 通讯作者: Isaacson RL

Additional file 2: of Structural complexity of the co-chaperone SGTA: a conserved C-terminal region is implicated in dimerization and substrate quality control

附加文件 2：共伴侣 SGTA 的结构复杂性：保守的 C 末端区域涉及二聚化和底物质量控制

• DOI: 10.6084/m9.figshare.6807905
• 发表时间: 2018
• 作者: MartA­Nez-Lumbreras S

Additional file 5: of Structural complexity of the co-chaperone SGTA: a conserved C-terminal region is implicated in dimerization and substrate quality control

附加文件 5：共伴侣 SGTA 的结构复杂性：保守的 C 末端区域涉及二聚化和底物质量控制

• DOI: 10.6084/m9.figshare.6807962
• 发表时间: 2018
• 作者: MartA­Nez-Lumbreras S

Solution structure of the SGTA dimerisation domain and investigation of its interactions with the ubiquitin-like domains of BAG6 and UBL4A.

• DOI: 10.1371/journal.pone.0113281
• 发表时间: 2014
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Darby JF;Krysztofinska EM;Simpson PJ;Simon AC;Leznicki P;Sriskandarajah N;Bishop DS;Hale LR;Alfano C;Conte MR;Martínez-Lumbreras S;Thapaliya A;High S;Isaacson RL
• 通讯作者: Isaacson RL

Additional file 3: of Structural complexity of the co-chaperone SGTA: a conserved C-terminal region is implicated in dimerization and substrate quality control

附加文件 3：共伴侣 SGTA 的结构复杂性：保守的 C 末端区域涉及二聚化和底物质量控制

• DOI: 10.6084/m9.figshare.6807923
• 发表时间: 2018
• 作者: MartA­Nez-Lumbreras S