Trails of migration out of Africa in harmful mutations of the First Peoples

原住民有害突变中走出非洲的迁徙轨迹

• 批准号: DP180100089
• 负责人: Dr Subashchandran Sankarasubramanian
• 金额: $ 27.95万
• 依托单位: University of the Sunshine Coast
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-02-22 至 2023-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP180100089
• 关键词: Trails; migration; out; Africa; harmful

This project aims to study harmful mutations specific to Indigenous populations. The process of migration out of Africa has left its footprints in the mutations present in world populations. By investigating these unique signatures, this project aims to characterise the harmful mutations specific to Aboriginal Australians using the whole genome sequences of the First Peoples. The expected outcomes will benefit future Aboriginal health research to better understand the mutations associated with various genetic diseases.

该项目旨在研究原住民特有的有害突变。 离开非洲的移民过程在世界人口的突变中留下了足迹。 通过研究这些独特的特征，该项目旨在利用原住民的全基因组序列来表征澳大利亚原住民特有的有害突变。预期结果将有利于未来的原住民健康研究，以更好地了解与各种遗传疾病相关的突变。