The wheat Diverse MAGIC platform: Community Access to Resources, Protocols and Tools

小麦 Diverse MAGIC 平台：社区获取资源、协议和工具

• 批准号: BB/M011666/1
• 负责人: James Cockram
• 金额: $ 65.98万
• 依托单位: National Institute of Agricultural Botany
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2015
• 资助国家: 英国
• 起止时间: 2015 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FM011666%2F1
• 关键词: wheat; Diverse; MAGIC; platform; Community

ContextWheat is the UK's most important crop, covering 1.6 million hectares and with an annual harvest worth £1.6 billion. Globally, demand for wheat is rising rapidly: it is estimated that by 2050, yield must rise by 60%. The best way to achieve gains in the key wheat breeding targets is to develop improved varieties. The ongoing revolution in genetic and molecular tools for wheat breeding is poised to deliver step changes in wheat genetic gain. However, comparatively little investment has been focused on the development of suitable biological resources to best take advantage of these tools. This project builds on previous publicly-funded investment in a state-of-the-art wheat biological platform: the Multiparent Advanced Generation Inter-Cross (MAGIC) population (termed, 'Diverse MAGIC'). Created over four years by inter-crossing 16 UK wheat varieties over multiple generations, the resulting population of over 600 lines represents a unique resource within the UK and worldwide. By capturing large amounts of genetic variation (from the 16 parents) and efficiently reshuffling these over multiple generations of crossing, the population is well placed to serve as a central resource for a broad spectrum of the UK wheat bioscience community.Aims and objectivesThis project brings together expertise from the plant and animal MAGIC sectors, to develop Diverse MAGIC into an integrated community platform for wheat genetics and breeding. This will be achieved by developing Diverse MAGIC resources, tools and community engagement programs that will enable effective use of Diverse MAGIC within the UK community. Specifically, it will:1) Enlarge the Diverse MAGIC population to 800 lines.2) Provide access to Diverse MAGIC seed.3) Establish a catalogue of genetic and phenotypic variation present in the 16 MAGIC parents.4) Provide baseline field phenotype and high-density genotype data on the whole population.5) Develop bioinformatic and software tools tailored to wheat MAGIC.6) Provide dissemination and training events to promote uptake of MAGIC in wheat.7) Establish and promote Diverse MAGIC 'community phenotyping' events.8) Collate the wheat MAGIC resources generated, and make freely accessible via the project website.Applications and benefitsThe biological and supporting resources generated by this project will stimulate new research, amplify output from existing wheat programs, and aid the translation of scientific discoveries to breeders, farmers and processors. The Diverse MAGIC resource complements existing UK wheat resources for gene validation, and will help promote collaborative research within the crop genetics sector.

ContextWheat是英国最重要的作物，占地160万公顷，每年收获价值16亿英镑。从全球来看，对小麦的需求正在迅速增长：据估计，到2050年，产量必须提高60%。要实现小麦育种重点目标的最佳途径是培育优良品种。小麦育种的遗传和分子工具正在发生革命，这将使小麦遗传增益发生阶段性变化。然而，相对较少的投资集中在开发适当的生物资源，以最好地利用这些工具。该项目建立在之前对最先进的小麦生物平台的公共资助投资的基础上：多亲本高级世代间杂交（MAGIC）群体（称为“多样化MAGIC”）。该品种是在四年多的时间里通过16个英国小麦品种多代杂交而产生的，所产生的600多个品系代表了英国和全球的独特资源。通过捕捉大量的遗传变异（来自16个亲本）并通过多代杂交有效地重新洗牌，该群体处于有利地位，可以作为英国小麦生物科学界广泛的核心资源。Aims and objectivesThis project汇集了植物和动物MAGIC部门的专业知识，将Diverse MAGIC发展成为小麦遗传和育种的综合社区平台。这将通过开发Diverse MAGIC资源、工具和社区参与计划来实现，这些计划将使Diverse MAGIC能够在英国社区内有效使用。具体而言，它将：1）将多样化MAGIC群体扩大到800个品系。2）提供多样化MAGIC种子。3）建立16个MAGIC亲本中存在的遗传和表型变异目录。4）提供整个群体的基线田间表型和高密度基因型数据。5）开发针对小麦MAGIC的生物信息学和软件工具。6）提供传播和培训活动，以促进小麦对MAGIC的吸收。7）建立和促进多样化MAGIC“社区表型”活动。8）整理产生的小麦MAGIC资源，并通过项目网站免费访问。应用和效益本项目产生的生物和支持资源将刺激新的研究，扩大现有小麦项目的产量，帮助育种者、农民和加工者将科学发现转化为成果。Diverse MAGIC资源补充了英国现有的小麦资源用于基因验证，并将有助于促进作物遗传学领域的合作研究。

项目成果

Achieving sustainable cultivation of wheat Volume 1

实现小麦的可持续种植第 1 卷

• DOI: 10.19103/as.2016.0004.05
• 发表时间: 2017
• 作者: Bentley A

Determining Phenological Patterns Associated with the Onset of Senescence in a Wheat MAGIC Mapping Population.

• DOI: 10.3389/fpls.2016.01540
• 发表时间: 2016
• 期刊: Frontiers in plant science
• 影响因子: 5.6
• 作者: Camargo AV;Mott R;Gardner KA;Mackay IJ;Corke F;Doonan JH;Kim JT;Bentley AR
• 通讯作者: Bentley AR

A roadmap for gene functional characterisation in wheat

小麦基因功能表征路线图

• DOI: 10.7287/peerj.preprints.26877v1
• 发表时间: 2018
• 作者: Adamski N

Multi-trait ensemble genomic prediction and simulations of recurrent selection highlight importance of complex trait genetic architecture for long-term genetic gains in wheat

多性状整体基因组预测和循环选择模拟强调了复杂性状遗传结构对于小麦长期遗传增益的重要性

• DOI: 10.1093/insilicoplants/diad002
• 发表时间: 2023
• 期刊: in silico Plants
• 影响因子: 3.1
• 作者: Fradgley N

Effects of breeding history and crop management on the root architecture of wheat

育种史和作物管理对小麦根系结构的影响

• DOI: 10.1101/2020.02.25.964338
• 发表时间: 2020
• 作者: Fradgley N