Drivers of effective T cell immunity
Drivers of effective T cell immunity
批准号:
FT170100174
负责人:
Prof Nicole La Gruta
金额:
$71.24万
依托单位:
依托单位国家:
澳大利亚
项目类别:
ARC Future Fellowships
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2021-12-31
中文摘要
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英文摘要
This project aims to investigate the mechanisms underpinning an effective immune response. In doing so, the project expects to decipher the various determinants of T cell immunity and explore how these determinants are integrated to generate effective immunity. The project will use a multidisciplinary approach to investigate antigen abundance and developmental, structural, and molecular aspects of T cells, expecting to significantly enhance our fundamental understanding of mechanisms underpinning functional T cell responses, build interdisciplinary collaborations, and significantly advance the field of T cell biology.
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会议论文
The Role of Lck/CD8 Association in Negatively Regulating T cell Activation
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批准号:DP230102412
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项目类别:Discovery Projects
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资助金额:$59.91万
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财政年份:2023
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负责人:Prof Nicole La Gruta
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依托单位:
Exceptions Prove the Rule: How Antigen Recognition Drives T cell Activation
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批准号:DP200102776
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项目类别:Discovery Projects
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资助金额:$41.44万
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财政年份:2020
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负责人:Prof Nicole La Gruta
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依托单位:
A molecular investigation into the naïve T cell repertoire
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批准号:DP170103631
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项目类别:Discovery Projects
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资助金额:$38.36万
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财政年份:2017
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负责人:Prof Nicole La Gruta
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依托单位:
Determinants of CTL recruitment into the immune response
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批准号:nhmrc : 1046333
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项目类别:Project Grants
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资助金额:$31.65万
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财政年份:2013
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负责人:Prof Nicole La Gruta
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依托单位:
Direct characterisation of naive epitope-specific T cell populations and their influence on immune responses
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批准号:nhmrc : 628316
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项目类别:NHMRC Project Grants
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资助金额:$21.0万
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财政年份:2010
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负责人:Prof Nicole La Gruta
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依托单位:
The role of antigen dose and T cell repertoire in determining CD8+ T cell immunodominance hierarchies
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批准号:nhmrc : 454770
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项目类别:Career Development Fellowships
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资助金额:$29.58万
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财政年份:2007
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负责人:Prof Nicole La Gruta
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依托单位:
Antigen dose and TCR repertoire in CD8+ T cell immunodominance hierarchies
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批准号:nhmrc : 454595
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项目类别:NHMRC Project Grants
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资助金额:$37.27万
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财政年份:2007
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负责人:Prof Nicole La Gruta
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依托单位:
The role of T cell receptor avidity in determining T cell repertoires and responses
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批准号:nhmrc : 350395
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项目类别:NHMRC Project Grants
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资助金额:$31.51万
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财政年份:2005
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负责人:Prof Nicole La Gruta
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依托单位:
国内基金
海外基金
多跳无线 MESH 网络中 QoS 保障算法的研究设计和性能分析
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批准号:60902041
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项目类别:青年科学基金项目
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资助金额:20.0万元
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批准年份:2009
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负责人:杨旸
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依托单位: