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Magnesium Network (MAG-NET): Integrating Soil-Crop-Animal Pathways to Improve Ruminant Health

镁网络 (MAG-NET)：整合土壤-作物-动物途径以改善反刍动物健康

基本信息

批准号：
BB/N004302/1
负责人：
Martin Roger Broadley
金额：
$ 73.11万
依托单位：
University of Nottingham
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2016
资助国家：
英国
起止时间：
2016 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=BB%2FN004302%2F1
关键词：
Magnesium Network MAG NET Integrating

项目摘要

Magnesium (Mg) plays an important role in many basic processes in living cells, and is therefore essential for animal health. Low Mg status (hypomagnesaemia) gives rise to conditions called tetany, or staggers, in ruminants like cattle and sheep. These conditions are remarkably widespread among ruminants in Europe, often with high fatality rates. Avoiding hypomagnesaemia is therefore important for animal welfare and farm business profitability. Typically the condition is managed by use of feed mixes or dietary supplements or by directly administering Mg to animals as a medicine. However, these approaches are costly and can be inefficient and ineffective. Another approach is to ensure that the grass grazed by animals in the field or eaten as hay or silage provides a good source of Mg. This approach is under-developed in UK agriculture, as is forage fertilizer management. To develop these approaches requires three advances. First, we must understand the natural variation in the capacity of the soil to supply Mg, caused by differences across the country in the properties of the soil and the composition of the rocks from which they are derived. Second, we must understand how farmers currently use Mg in a range of enterprises as supplements, additives, fertilizers and veterinary interventions. Third, we must understand the mechanisms by which Mg is transferred from soil to plant to animal and how these can be exploited. For example, forage grass varieties that accumulate more Mg were selected by plant breeders in the 1970/80s. For example, a variety of Italian ryegrass (Lolium multiflorum 'Magnet/RVP2067') which accumulates more Mg was selected in UK breeding programmes. This variety performed consistently across sites and was shown to improve ruminant Mg status in feeding studies. However, this trait has not since been pursued in modern hybrid or perennial ryegrass varieties now favoured by the sector. We aim to develop novel and resilient nutrient management strategies for Mg in the UK ruminant sectors. The primary nutritional focus of this project is Mg due to its strategic importance to the UK ruminant sector. However, new data, knowledge and management and communication tools arising from this project will apply to other nutrients/elements which are important for animal health. The project will therefore have wider potential to make animal production more efficient and resilient and will improve our wider understanding of landscape-scale processes. This project will draw on a range of scientific disciplines including soil chemistry, geology, statistics economics and plant sciences. The four primary objectives are: (1) to use varied soil data to map the regions of England, N. Ireland and Wales where the soil supply of Mg is likely to be insufficient (2) to develop new understanding of Mg transfers on the farm and how these are managed, (3) to develop genetic markers and crop management strategies to increase leaf Mg concentration in modern forage grasses, and (4) to integrate these streams of knowledge and information into a decision tool that allows the farmer to improve forage nutrient management at farm scale and also help advisors or policy makers to examine management options at regional scale. The tool will take into account the economic impact of nutrient management scenarios based upon delivery via mineral supplements or improved grazing management via enhanced nutritional forage profiles given local and regional soil conditions. Decision support will be delivered via a user-friendly web/smart-phone interface. User-defined inputs will include spatial data (soil characteristics, climate, etc.), choice of grass variety, fertiliser-management, supplement use, and economic costs. Outputs will enable the economic benefits of the various Mg nutrition options to be compared and communicated, at farm-to-regional scales.

镁 (Mg) 在活细胞的许多基本过程中发挥着重要作用，因此对动物健康至关重要。低镁状态（低镁血症）会导致牛和羊等反刍动物出现手足抽搐或摇摇欲坠的情况。这些病症在欧洲的反刍动物中非常普遍，通常死亡率很高。因此，避免低镁血症对于动物福利和农场企业盈利能力非常重要。通常，通过使用混合饲料或膳食补充剂或直接向动物施用镁作为药物来控制病情。然而，这些方法成本高昂，而且效率低下且效果不佳。另一种方法是确保动物在田间放牧或作为干草或青贮饲料食用的草提供良好的镁来源。这种方法在英国农业中尚未得到充分发展，饲料肥料管理也是如此。开发这些方法需要三项进展。首先，我们必须了解土壤供应镁的能力的自然变化，这是由于全国各地土壤性质和岩石成分的差异造成的。其次，我们必须了解农民目前如何在一系列企业中使用镁作为补充剂、添加剂、肥料和兽医干预措施。第三，我们必须了解镁从土壤转移到植物再到动物的机制以及如何利用这些机制。例如，植物育种家在 20 世纪 70 至 80 年代选择了积累更多镁的饲草品种。例如，英国育种计划中选择了积累更多镁的多种意大利黑麦草（Lolium multiflorum 'Magnet/RVP2067'）。该品种在各个地点表现一致，并且在饲喂研究中显示可以改善反刍动物的镁状态。然而，此后这一特性并没有在目前受到该行业青睐的现代杂交或多年生黑麦草品种中得到体现。我们的目标是为英国反刍动物行业的镁制定新颖且有弹性的营养管理策略。该项目的主要营养重点是镁，因为它对英国反刍动物行业具有战略重要性。然而，该项目产生的新数据、知识、管理和沟通工具将适用于对动物健康重要的其他营养素/元素。因此，该项目将具有更广泛的潜力，使动物生产更加高效和有弹性，并将提高我们对景观规模过程的更广泛的理解。该项目将利用一系列科学学科，包括土壤化学、地质学、统计经济学和植物科学。四个主要目标是：(1) 使用不同的土壤数据来绘制英格兰、北爱尔兰和威尔士土壤镁供应可能不足的地区地图 (2) 对农场的镁转移以及如何管理镁转移有新的认识，(3) 开发遗传标记和作物管理策略，以提高现代饲草中叶片镁的浓度，以及 (4) 将这些知识和信息流整合到决策工具中，以允许帮助农民改善农场规模的饲料养分管理，并帮助顾问或政策制定者检查区域规模的管理方案。该工具将考虑营养管理方案的经济影响，这些方案基于通过矿物质补充剂提供或根据当地和区域土壤条件通过增强营养草料配置来改善放牧管理。决策支持将通过用户友好的网络/智能手机界面提供。用户定义的输入将包括空间数据（土壤特征、气候等）、草品种的选择、肥料管理、补充品使用和经济成本。产出将使各种镁营养方案的经济效益能够在农场到区域范围内进行比较和交流。

项目成果

期刊论文数量（8）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

A reconnaissance survey of farmers' awareness of hypomagnesaemic tetany in UK cattle and sheep farms

DOI：
10.1371/journal.pone.0223868
发表时间：
2019-10-11
期刊：
PLOS ONE
影响因子：
3.7
作者：
Kumssa, Diriba B.;Penrose, Beth;Ander, E. Louise
通讯作者：
Ander, E. Louise

Magnesium and calcium overaccumulate in the leaves of a schengen3 mutant of Brassica rapa.

镁和钙过于积聚在脑脑的Schengen3突变体的叶片中。

DOI：
10.1093/plphys/kiab150
发表时间：
2021-07-06
期刊：
Plant physiology
影响因子：
7.4
作者：
Alcock TD;Thomas CL;Ó Lochlainn S;Pongrac P;Wilson M;Moore C;Reyt G;Vogel-Mikuš K;Kelemen M;Hayden R;Wilson L;Stephenson P;Østergaard L;Irwin JA;Hammond JP;King GJ;Salt DE;Graham NS;White PJ;Broadley MR
通讯作者：
Broadley MR

Revisiting variation in leaf magnesium concentrations in forage grasses for improved animal health

重新审视饲草叶镁浓度的变化以改善动物健康